TABLE 1
FROM:
Recruitment of leukemic cells from G0 phase of the cell cycle by interferons results in conversion of resistance to daunorubicin
I Jedema, R M Y Barge, B A Nijmeijer, R Willemze and J H F Falkenburg
BACK TO ARTICLETable 1. Cell cycle distribution after in vivo chemotherapy
| Pt | Gender/age | FAB class | Time point | Cell cycle distribution | WBC (106/ml) | % blasts | % lymphocytes | ||
|---|---|---|---|---|---|---|---|---|---|
| G0 | G1 | S/G2/M | |||||||
| 1 | m/29 | M4 | Day 0 | 64 | 30 | 6 | 30 | 85 | 9 |
| Day 1 | 75 | 23 | 2 | 6.4 | 82 | 10 | |||
| Day 2 | 80 | 18 | 2 | 1.7 | 58 | 31 | |||
| Day 3 | 92 | 7 | 1 | 0.7 | 40 | 59 | |||
| 2 | f/45 | M5 | Day 0 | 80 | 13 | 7 | 38.3 | 90 | 4 |
| Day 1 | 54 | 44 | 2 | 7.9 | 82 | 12 | |||
| Day 2 | ND | ND | ND | ND | ND | ND | |||
| Day 3 | 94 | 4 | 2 | 0.5 | 57 | 21 | |||
| 3 | m/35 | M1 | Day 0 | 52 | 45 | 3 | 86.2 | 95 | 1 |
| Day 1 | 85 | 14 | 1 | 76.6 | 91 | 4 | |||
| Day 2 | ND | ND | ND | ND | ND | ND | |||
| Day 3 | 72 | 28 | 0 | 5.8 | 74 | 9 | |||
WBC=white blood cell count; ND=not done. The cell cycle distribution within the total nuclear cell population is listed at diagnosis and at 1, 2, and 3 days after chemotherapy administration. Owing to logistic problems, day 2 is missing in patients 2 and 3.
