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 |
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| Spotlight on IMATINIB as a Model for Signal Transduction Inhibitors |
|
Early reduction of BCR-ABL mRNA transcript levels predicts cytogenetic response in chronic phase CML patients treated with imatinib after failure of interferon  FREE |
| K Merx, M C Müller, S Kreil, T Lahaye, P Paschka, C Schoch, A Weisser, C Kuhn, U Berger, H Gschaidmeier, R Hehlmann & A Hochhaus |
| Abstract Full Article PDF |
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| 1579 |
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| Spotlight on IMATINIB as a Model for Signal Transduction Inhibitors |
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| Effects of imatinib on bone marrow engraftment in syngeneic mice FREE |
| J Hoepfl, C Miething, R Grundler, K S Götze, C Peschel & J Duyster |
| Abstract Full Article PDF |
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| 1584 |
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| Spotlight on IMATINIB as a Model for Signal Transduction Inhibitors |
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| Interleukin-3 protects Bcr-Abl-transformed hematopoietic progenitor cells from apoptosis induced by Bcr-Abl tyrosine kinase inhibitors FREE |
| J F Dorsey, J M Cunnick, R Lanehart, M Huang, A J Kraker, K N Bhalla, R Jove & J Wu |
| Abstract Full Article PDF |
|
| 1589 |
|
| Spotlight on Molecular Targeted Therapy |
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| Sphingosine 1-phosphate as a therapeutic agent FREE |
| S Spiegel & R Kolesnick |
| Abstract Full Article PDF |
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| 1596 |
|
| Review |
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| CD34+ or CD34-: which is the more primitive? FREE |
| M Engelhardt, M Lübbert & Y Guo |
| Abstract Full Article PDF |
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| 1603 |
|
| Original Manuscripts |
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| Clinical efficacy and antiangiogenic activity of thalidomide in myelofibrosis with myeloid metaplasia. A pilot study FREE |
| P P Piccaluga, G Visani, S A Pileri, S Ascani, T Grafone, A Isidori, M Malagola, C Finelli, G Martinelli, P Ricci, M Baccarani & S Tura |
| Abstract Full Article PDF |
|
| 1609 |
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| Chemotherapy only compared to chemotherapy followed by transplantation in high risk myelodysplastic syndrome and secondary acute myeloid leukemia; two parallel studies adjusted for various prognostic factors FREE |
| M Oosterveld, P Muus, S Suciu, C Koller, G Verhoef, B Labar, P Wijermans, C Aul, D Fière, D Selleslag, R Willemze, A Gratwohl, A Ferrant, F Mandelli, J Cortes, T de Witte & E Estey for the EORTC, EBMT, SAKK, GIMEMA Leukemia Groups & the MD Anderson Cancer Center |
| Abstract Full Article PDF |
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| 1615 |
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| Acute megakaryoblastic leukemia: experience of GIMEMA trials FREE |
| L Pagano, A Pulsoni, M Vignetti, L Mele, L Fianchi, M C Petti, S Mirto, P Falcucci, P Fazi, G Broccia, G Specchia, F Di Raimondo, L Pacilli, P Leoni, S Ladogana, E Gallo, A Venditti, G Avanzi, A Camera, V Liso, G Leone & F Mandelli for the GIMEMA |
| Abstract Full Article PDF |
|
| 1622 |
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| Antibody-targeted chemotherapy of older patients with acute myeloid leukemia in first relapse using Mylotarg (gemtuzumab ozogamicin) FREE |
| R A Larson, M Boogaerts, E Estey, C Karanes, E A Stadtmauer, E L Sievers, P Mineur, J M Bennett, M S Berger, C B Eten, M Munteanu, M R Loken, J J M van Dongen, I D Bernstein & F R Appelbaum for the Mylotarg Study Group |
| Abstract Full Article PDF |
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| 1627 |
|
| Gene transfer of CD154 and IL12 cDNA induces an anti-leukemic immunity in a murine model of acute leukemia FREE |
| A Saudemont, G Buffenoir, A Denys, P Desreumaux, N Jouy, D Hetuin, F Bauters, P Fenaux & B Quesnel |
| Abstract Full Article PDF |
|
| 1637 |
|
| Transduction of acute myeloid leukemia cells with third generation self-inactivating lentiviral vectors expressing CD80 and GM-CSF: effects on proliferation, differentiation, and stimulation of allogeneic and autologous anti-leukemia immune responses FREE |
| R C Koya, N Kasahara, V Pullarkat, A M Levine & R Stripecke |
| Abstract Full Article PDF |
|
| 1645 |
|
| Persisting multilineage transgene expression in the clonal progeny of a hematopoietic stem cell FREE |
| Z Li, B Fehse, B Schiedlmeier, J Düllmann, O Frank, A R Zander, W Ostertag & C Baum |
| Abstract Full Article PDF |
|
| 1655 |
|
| Farnesyl transferase inhibitor R115777 induces apoptosis of human myeloma cells FREE |
| S Le Gouill, C Pellat-Deceunynck, J-L Harousseau, M-J Rapp, N Robillard, R Bataille & M Amiot |
| Abstract Full Article PDF |
|
| 1664 |
|
| Minimal residual disease (MRD) status prior to allogeneic stem cell transplantation is a powerful predictor for post-transplant outcome in children with ALL FREE |
| P Bader, J Hancock, H Kreyenberg, N J Goulden, D Niethammer, A Oakhill, C G Steward, R Handgretinger, J F Beck & T Klingebiel |
| Abstract Full Article PDF |
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| 1668 |
|
| Therapy-related myelodysplastic syndrome after autologous stem cell transplantation for breast cancer FREE |
| G Nichols, K de Castro, L-X Wei, M Griffin, N Lin, A Oratzi, V V V S Murty, A Troxel, L Vahdat & C Hesdorffer |
| Abstract Full Article PDF |
|
| 1673 |
|
| Correlation of bone marrow angiogenesis and mast cells with tryptase activity in myelodysplastic syndromes FREE |
| D Ribatti, G Polimeno, A Vacca, A Marzullo, E Crivellato, B Nico, G Lucarelli & F Dammacco |
| Abstract Full Article PDF |
|
| 1680 |
|
| Infant acute lymphoblastic leukemia - combined cytogenetic, immunophenotypical and molecular analysis of 77 cases FREE |
| A Borkhardt, C Wuchter, S Viehmann, S Pils, A Teigler-Schlegel, M Stanulla, M Zimmermann, W-D Ludwig, G Janka-Schaub, M Schrappe & J Harbott |
| Abstract Full Article PDF |
|
| 1685 |
|
| Surface membrane antigen expression changes induced in vitro by exogenous growth factors in chronic lymphocytic leukemia cells FREE |
| J Vilpo, J Hulkkonen, M Hurme & L Vilpo |
| Abstract Full Article PDF |
|
| 1691 |
|
| Prognostic significance of FLT3 internal tandem repeat in patients with de novo acute myeloid leukemia treated with reinforced courses of chemotherapy FREE |
| N Boissel, J M Cayuela, C Preudhomme, X Thomas, N Grardel, X Fund, I Tigaud, E Raffoux, P Rousselot, F Sigaux, L Degos, S Castaigne, P Fenaux & H Dombret |
| Abstract Full Article PDF |
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| 1699 |
|
| Exposure to low concentrations of etoposide reduces the apoptotic capability of leukaemic cell lines FREE |
| W M Liu, P R Oakley & S P Joel |
| Abstract Full Article PDF |
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| 1705 |
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| Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins FREE |
| M Konopleva, S Konoplev, W Hu, A Y Zaritskey, B V Afanasiev & M Andreeff |
| Abstract Full Article PDF |
|
| 1713 |
|
| High Bcr-Abl expression prevents the translocation of Bax and Bad to the mitochondrion FREE |
| K Keeshan, T G Cotter & S L McKenna |
| Abstract Full Article PDF |
|
| 1725 |
|
| CD20-induced B cell death can bypass mitochondria and caspase activation FREE |
| L E van der Kolk, L M Evers, C Omene, S M A Lens, S Lederman, R A W van Lier, M H J van Oers & E Eldering |
| Abstract Full Article PDF |
|
| 1735 |
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| Incidence and significance of cryptic chromosome aberrations detected by fluorescence in situ hybridization in acute myeloid leukemia with normal karyotype FREE |
| A Cuneo, R Bigoni, F Cavazzini, A Bardi, M G Roberti, P Agostini, E Tammiso, N Ciccone, M Mancini, M Nanni, R De Cuia, M Divona, R La Starza, B Crescenzi, N Testoni, G Rege Cambrin, C Mecucci, F Lo Coco, G Saglio & G Castoldi |
| Abstract Full Article PDF |
|
| 1745 |
|
| Large deletions 5' to the ETO breakpoint are recurrent events in patients with t(8;21) acute myeloid leukemia FREE |
| C Godon, J Proffitt, N Dastugue, M Lafage-Pochitaloff, M-J Mozziconacci, P Talmant, M Hackbarth, R Bataille & H Avet-Loiseau |
| Abstract Full Article PDF |
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| 1752 |
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| The human promyelocytic leukemia zinc finger gene is regulated by the Evi-1 oncoprotein and a novel guanine-rich site binding protein FREE |
| S Takahashi & J D Licht |
| Abstract Full Article PDF |
|
| 1755 |
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| Retinoic acid receptor antagonism in vivo expands the numbers of precursor cells during granulopoiesis FREE |
| C R Walkley, Y-D Yuan, R A S Chandraratna & G A McArthur |
| Abstract Full Article PDF |
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| 1763 |
|
| Nuclear factor-erythroid 2 (NF-E2) expression in normal and malignant megakaryocytopoiesis FREE |
| L Catani, N Vianelli, M Amabile, L Pattacini, L Valdrè, M E Fagioli, M Poli, L Gugliotta, P Moi, M G Marini, G Martinelli, S Tura & M Baccarani |
| Abstract Full Article PDF |
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| 1773 |
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| Stromal cells from murine embryonic aorta-gonad-mesonephros region, liver and gut mesentery expand human umbilical cord blood-derived CAFCweek6 in extended long-term cultures FREE |
| N Kusadasi, R A J Oostendorp, W J L M Koevoet, E A Dzierzak & R E Ploemacher |
| Abstract Full Article PDF |
|
| 1782 |
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| HERG potassium channels are constitutively expressed in primary human acute myeloid leukemias and regulate cell proliferation of normal and leukemic hemopoietic progenitors FREE |
| S Pillozzi, M F Brizzi, M Balzi, O Crociani, A Cherubini, L Guasti, B Bartolozzi, A Becchetti, E Wanke, P A Bernabei, M Olivotto, L Pegoraro & A Arcangeli |
| Abstract Full Article PDF |
|
| 1791 |
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| Chemotherapy targeting methylthioadenosine phosphorylase (MTAP) deficiency in adult T cell leukemia (ATL) FREE |
| H Harasawa, Y Yamada, M Kudoh, K Sugahara, H Soda, Y Hirakata, H Sasaki, S Ikeda, T Matsuo, M Tomonaga, T Nobori & S Kamihira |
| Abstract Full Article PDF |
|
| 1799 |
|
| Schedule-dependent synergism and antagonism between methotrexate and cytarabine against human leukemia cell lines in vitro FREE |
| M Akutsu, Y Furukawa, S Tsunoda, T Izumi, K Ohmine & Y Kano |
| Abstract Full Article PDF |
|
| 1808 |
|
| Human AML cells in NOD/SCID mice: engraftment potential and gene expression FREE |
| R Lumkul, N-C Gorin, M T Malehorn, G T Hoehn, R Zheng, B Baldwin, D Small, S Gore, D Smith, P S Meltzer & C I Civin |
| Abstract Full Article PDF |
|
| 1818 |
|
| F-MuLV acceleration of myelomonocytic tumorigenesis in SV40 large T antigen transgenic mice is accompanied by retroviral insertion at Fli1 and a novel locus, Fim4 FREE |
| J Kone, J Arroyo, T Savinelli, S Lin, K Boyd, Y Wu, M Nimmakayalu, N G Copeland, N A Jenkins, M Qumsiyeh, P Hu, A Prescott, H Wu, L Yang, B Roe & A S Perkins |
| Abstract Full Article PDF |
|
| 1827 |
|
| Clinical activity of arsenic trioxide for the treatment of multiple myeloma FREE |
| N C Munshi, G Tricot, R Desikan, A Badros, M Zangari, A Toor, C Morris, E Anaissie & B Barlogie |
| Abstract Full Article PDF |
|
| 1835 |
|
| Long-term results (12 years) of high-dose therapy in 127 patients with de novo multiple myeloma FREE |
| P Moreau, R Misbahi, N Milpied, N Morineau, B Mahé, M Vigier, M J Rapp, R Bataille & J L Harousseau |
| Abstract Full Article PDF |
|
| 1838 |
|
| Alterations of the cyclin D1/pRb/p16INK4A pathway in multiple myeloma FREE |
| A Krämer, B Schultheis, J Bergmann, A Willer, U Hegenbart, A D Ho, H Goldschmidt & R Hehlmann |
| Abstract Full Article PDF |
|
| 1844 |
|
| Distribution of BCL2 breakpoints in follicular lymphoma and correlation with clinical features: specific subtypes or same disease? FREE |
| G Buchonnet, F Jardin, N Jean, P Bertrand, F Parmentier, S Tison, S Lepretre, N Contentin, P Lenain, A Stamatoullas-Bastard, H Tilly & C Bastard |
| Abstract Full Article PDF |
|
| 1852 |
|
| BCL-6 mRNA expression in higher grade transformation of follicle center lymphoma: correlation with somatic mutations in the 5' regulatory region of the BCL-6 gene FREE |
| I S Lossos, R Warnke & R Levy |
| Abstract Full Article PDF |
|
| 1857 |
|
| Correspondence |
|
| The novel t(11;12;18)(q21;q13;q21) represents a variant translocation of the t(11;18)(q21;q21) associated with MALT-type lymphoma FREE |
| J Dierlamm, E M Murga Penas, M Daibata, H Tagushi, K Hinz, M Baens, J Cools, G Schilling, L Michaux, P Marynen, I Miyoshi & D K Hossfeld |
| Abstract Full Article PDF |
|
| 1863 |
|
| Differential bone marrow aspirate DNA yields from commercial extraction kits FREE |
| R Aplenc, E Orudjev, J Swoyer, B Manke & T Rebbeck |
| Abstract Full Article PDF |
|
| 1865 |
|
| Mutation of the AML1/RUNX1 gene in a transient myeloproliferative disorder patient with Down syndrome FREE |
| T Taketani, T Taki, J Takita, R Ono, Y Horikoshi, Y Kaneko, M Sako, R Hanada, T Hongo & Y Hayashi |
| Abstract Full Article PDF |
|
| 1866 |
|
| DNA profiling and cytogenetic analysis of cell line WSU-CLL reveal cross-contamination with cell line REH (pre B-ALL) FREE |
| H G Drexler, H Quentmeier, W G Dirks, C C Uphoff & R A F MacLeod |
| Abstract Full Article PDF |
|
| 1868 |
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| Sustained complete remission of recurrent acute myeloid leukaemia with a single dose of gemtuzumab ozogamicin and low-dose interleukin-2 maintenance FREE |
| M P Radsak, H R Salih, M Sökler, L Kanz & C Denzlinger |
| Abstract Full Article PDF |
|
| 1870 |
|
| Complete remission in hypoplastic acute myeloid leukemia induced by G-CSF without chemotherapy: report on three cases FREE |
| S Nimubona, I Grulois, M Bernard, B Drénou, M Godard, R Fauchet & T Lamy |
| Abstract Full Article PDF |
|
| 1871 |
|
| Additional evidence of genetic changes in children with ALL and TEL/AML1 fusion gene FREE |
M Jaro ová, M Holzerova, V Mihál, J Blatn , I Lakomá, J Trka, Z Pikalová, O Hruák & K Indrák |
| Abstract Full Article PDF |
|
| 1873 |
|
| Cultures of myeloid progenitor cells in pediatric essential thrombocythemia FREE |
| L Florensa, L Zamora, C Besses, J J Ortega, P Bastida, T Toll, P Mayayo, B Espinet, F Solé, S Serrano & S Woessner |
| Abstract Full Article PDF |
|
| 1876 |
|
| Identification and characterization of rapidly dividing U937 clones with differential telomerase activity and gene expression profiles: role of c-Myc/Mad1 and Id/Ets proteins FREE |
| X Xiao, S K Phogat, I A Sidorov, J Yang, I Horikawa, D Prieto, J Adelesberger, R Lempicki, J C Barrett & D S Dimitrov |
| Abstract Full Article PDF |
|
| 1877 |
|
| Liposomal daunorubicin (DaunoXome) for treatment of relapsed meningeal acute myeloid leukemia FREE |
| P P Piccaluga, G Visani, G Martinelli, A Isidori, M Malagola, M Rondoni, M Baccarani & S Tura |
| Abstract Full Article PDF |
|
| 1880 |
|
| Increased risk of human herpesvirus-8 infection in patients with adult T cell leukemia/lymphoma in Okinawa FREE |
| J Miyagi, M Masuda, H Uezato, T Sawada, T Miyakuni, I Miyoshi & N Takasu |
| Abstract Full Article PDF |
|
| 1881 |
|
| In vitro glucocorticoid resistance in childhood leukemia correlates with receptor affinity determined at 37°C, but not with affinity determined at room temperature FREE |
| E G Haarman, G J L Kaspers, R Pieters, M M A Rottier, M L Den Boer, G E Janka-Schaub & A J P Veerman |
| Abstract Full Article PDF |
|
| 1882 |
|
| Treatment of HBV-carrying lymphoma patients with Rituximab and CHOP: a diagnostic and therapeutic challenge FREE |
| C Skrabs, C Müller, H Agis, C Mannhalter & U Jäger |
| Abstract Full Article PDF |
|
| 1884 |
|
| Mechanisms of resistance to nucleoside analogue chemotherapy in mantle cell lymphoma: a molecular case study FREE |
| T Reiman, K A Graham, J Wong, A R Belch, R Coupland, J Young, C E Cass & J R Mackey |
| Abstract Full Article PDF |
|
| 1886 |
|
| Therapy-related myelodysplastic syndrome or acute myelogenous leukemia in patients with acute promyelocytic leukemia (APL) FREE |
| G Garcia-Manero, H M Kantarjian, S Kornblau & E Estey |
| Abstract Full Article PDF |
|
| 1888 |
|
| Blastic variant of mantle cell lymphoma occurring in immunosuppressed patients FREE |
| L R Munro, P W Johnston, J R Goodlad & D J Culligan |
| Abstract Full Article PDF |
|
| 1888 |
|
| Reply to Munro et al FREE |
| M Bernard & T Lamy |
| Abstract Full Article PDF |
|
| 1889 |
|
| A potential role of erythropoietin in angiogenesis associated with myelodysplastic syndromes FREE |
| D Ribatti |
| Abstract Full Article PDF |
|
| 1890 |
|
| Response to letter from Dr Domenico Ribatti FREE |
| U Bunworasate, H Arnouk, H Minderman, K L O'Loughlin, S N J Sait, M Barcos, C C Stewart & M R Baer |
| Abstract Full Article PDF |
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| 1891 |
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| September 2002, Volume 16, Number 9 |
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