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| Spotlight on Chronic Lymphocytic Leukemia |
| Genetic susceptibility to chronic lymphocytic leukemia |
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| R S Houlston1, D Catovsky2 and M R Yuille2 |
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1Section of Cancer Genetics, Institute of Cancer Research, Sutton, UK
2Academic Department of Haematology and Cytogenetics, Institute of Cancer Research, Sutton, UK
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Correspondence to: R S Houlston, Section of Cancer Genetics, Institute of Cancer Research, 15 Cotswold Road, Sutton Surrey SM2 5NG UK; Fax: +44 208 722 4362 |
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| Abstract |
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There is increasing evidence that a subset of chronic lymphocytic leukemia is caused by an inherited predisposition. Here we review the evidence for an inherited predisposition, the characteristics of familial cases and evidence for the involvement of specific genes. Leukemia (2002) 16, 1008-1014. DOI: 10.1038/sj/leu/2402538 |
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| Keywords |
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inherited susceptibility; chronic lymphocytic leukemia |
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| Received 4 April 2001; accepted 20 September 2001 |
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| June 2002, Volume 16, Number 6, Pages 1008-1014 |
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