Figure 1 Patient 1 (a, b, c, d) and patient 2 (e, f, g, h). Bone marrow stained by May-Grünwald-Giensa. (a, b) Major myelodysplastic features and Auer rods (arrow) were seen for patient 1. (e) Major dyseosinopoiesis (bold arrow) and (f) Auer rods (arrow) in neutrophils for patient 2. Conventional cytogenetic. (c) inv(16)(p13;q22) in patient 1. (g) inv(16)(p13;q22) and + 8 inv (16) in patient 2. Arrow shows the derivative chromosome 16. FISH analysis using CBF dual-color probes. (d, h) In both patients a normal chromosome 16 detected by yellow fusion signal and a derivative chromosome 16 (arrow) harboring a green signal on the long arm and a red signal on the short arm can be seen.

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