¹St Jude Children's Research Hospital and University of Tennessee, TN, USA

²College of Medicine, Memphis, TN, USA

³Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA

⁴Children's Hospital, Harvard Medical School, Boston, MA, USA

⁵College of Pharmacy, Memphis, TN, USA

⁶Department of Pediatrics, University of Milan-Bicocca, Ospedale San Gerardo, Monza, Italy

Correspondence to: C-H Pui, St Jude Children's Research Hospital, 332 N Lauderdale Street, Memphis, TN 38105, USA; Fax: 901-521-9005

clinical trials; risk factors; glucocorticoids; Philadelphia chromosome; minimal residual disease; new agents