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January 2001, Volume 15, Number 1

Table of Contents

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Spotlight on Apoptosis
Development of cyclin-dependent kinase modulators as novel therapeutic approaches for hematological malignancies FREE
A M Senderowicz
Abstract  |  Full text  |  PDF 1
Editorial
Hypothesis: Phenol and hydroquinone derived mainly from diet and gastrointestinal flora activity are causal factors in leukemia FREE
T A McDonald, N T Holland, C Skibola, P Duramad & M T Smith
Abstract  |  Full text  |  PDF 10
Reviews
Molecular signals in anti-apoptotic survival pathways FREE
D M O'Gorman & T G Cotter
Abstract  |  Full text  |  PDF 21
Chronic neutrophilic leukemia (CNL): a clinical, pathologic and cytogenetic study FREE
M A Elliott, G W Dewald, A Tefferi & C A Hanson
Abstract  |  Full text  |  PDF 35
Original Manuscripts
Second malignancy after treatment of childhood acute myeloid leukemia FREE
W Leung, R C Ribeiro, M Hudson, X Tong, D K Srivastava, J E Rubnitz, J T Sandlund, B I Razzouk, W E Evans & C-H Pui
Abstract  |  Full text  |  PDF 41
Extramedullary infiltrates at diagnosis have no prognostic significance in children with acute myeloid leukaemia FREE
M M Bisschop, T Révész, M Bierings, J F van Weerden, E R van Wering, K Hählen & A van der Does-van den Berg
Abstract  |  Full text  |  PDF 46
Purified autologous grafting in childhood acute lymphoblastic leukemia in second remission: evidence for long-term clinical and molecular remissions FREE
A Balduzzi, G Gaipa, S Bonanomi, M Dassi, P Perseghin, F Buscemi, E D'Aniello, A Rovelli, R Schirò, D Longoni, A Rambaldi, C Uderzo & A Biondi
Abstract  |  Full text  |  PDF 50
Comparison of outcome in acute myelogenous leukemia patients with translocation (8;21) found by standard cytogenetic analysis and patients with AML1/ETO fusion transcript found only by PCR testing FREE
J E Sarriera, M Albitar, Z Estrov, C Gidel, R Aboul-Nasr, T Manshouri, S Kornblau, K-S Chang, H Kantarjian & E Estey
Abstract  |  Full text  |  PDF 57
Proliferating status of peripheral blood progenitor cells from patients with BCR/ABL-positive chronic myelogenous leukemia FREE
A Krämer, H Löffler, J Bergmann, A Hochhaus & R Hehlmann
Abstract  |  Full text  |  PDF 62
Modulation of ara-CTP levels by fludarabine and hydroxyurea in leukemic cells FREE
M Ahlmann, C Lanvers, K Lümkemann, C Rössig, A Freund, M Baumann & J Boos
Abstract  |  Full text  |  PDF 69
6-Mercaptopurine dosage and pharmacokinetics influence the degree of bone marrow toxicity following high-dose methotrexate in children with acute lymphoblastic leukemia FREE
K Schmiegelow & U Bretton-Meyer
Abstract  |  Full text  |  PDF 74
Cyclosporin increases cellular idarubicin and idarubicinol concentrations in relapsed or refractory AML mainly due to reduced systemic clearance FREE
M Smeets, R Raymakers, P Muus, G Vierwinden, P Linssen, R Masereeuw & T de Witte
Abstract  |  Full text  |  PDF 80
Fusion of MOZ and p300 histone acetyltransferases in acute monocytic leukemia with a t(8;22)(p11;q13) chromosome translocation FREE
I Kitabayashi, Y Aikawa, A Yokoyama, F Hosoda, M Nagai, N Kakazu, T Abe & M Ohki
Abstract  |  Full text  |  PDF 89
Detection of E2A translocations in leukemias via fluorescence in situ hybridization FREE
T Boomer, M Varella-Garcia, L McGavran, L Meltesen, A S Olsen & S P Hunger
Abstract  |  Full text  |  PDF 95
C/EBPepsilon -/- mice: increased rate of myeloid proliferation and apoptosis FREE
W Verbeek, M Wächter, J Lekstrom-Himes & H P Koeffler
Abstract  |  Full text  |  PDF 103
The inositol 5-phosphatase SHIP is expressed as 145 and 135 kDa proteins in blood and bone marrow cells in vivo, whereas carboxyl-truncated forms of SHIP are generated by proteolytic cleavage in vitro FREE
S Horn, J Meyer, J Heukeshoven, B Fehse, C Schulze, S Li, J Frey, S Poll, C Stocking & M Jücker
Abstract  |  Full text  |  PDF 112
Immunoglobulin lambda isotype gene rearrangements in B cell malignancies FREE
T Tümkaya, M van der Burg, R Garcia Sanz, M Gonzalez Diaz, A W Langerak, J F San Miguel & J J M van Dongen
Abstract  |  Full text  |  PDF 121
HLA class I antigen cell surface expression is preserved on acute myeloid leukemia blasts at diagnosis and at relapse FREE
M Wetzler, M R Baer, S J Stewart, K Donohue, L Ford, C C Stewart, E A Repasky & S Ferrone
Abstract  |  Full text  |  PDF 128
Quantification of minimal residual disease in children with oligoclonal B-precursor acute lymphoblastic leukemia indicates that the clones that grow out during relapse already have the slowest rate of reduction during induction therapy FREE
V de Haas, O J H M Verhagen, A E G Kr von dem Borne, W Kroes, H van den Berg & C E van der Schoot
Abstract  |  Full text  |  PDF 134
Development and characterization of T cell leukemia cell lines established from SCL/LMO1 double transgenic mice FREE
D S Chervinsky, D H Lam, X-F Zhao, M P Melman & P D Aplan
Abstract  |  Full text  |  PDF 141
Establishment of a follicular lymphoma cell line (FLK-1) dependent on follicular dendritic cell-like cell line HK FREE
Y Kagami, J Jung, Y S Choi, K Osumi, S Nakamura, Y Morishima & M Seto
Abstract  |  Full text  |  PDF 148
Hypermethylation of p16INK4A gene promoter during the progression of plasma cell dyscrasia FREE
T Uchida, T Kinoshita, T Ohno, H Ohashi, H Nagai & H Saito
Abstract  |  Full text  |  PDF 157
Bio-technical Methods Section (BTS)
Quantification of minimal residual disease in T-lineage acute lymphoblastic leukemia with the TAL-1 deletion using a standardized real-time PCR assay FREE
X Chen, Q Pan, P Stow, F G Behm, R Goorha, C-H Pui & G A M Neale
Abstract  |  Full text  |  PDF 166
Angiogenesis in multiple myeloma: correlation between in vitro endothelial colonies growth (CFU-En) and clinical-biological features FREE
M Dominici, D Campioni, F Lanza, M Luppi, P Barozzi, S Pauli, R Milani, F Cavazzini, M Punturieri, R Trovato, G Torelli & G Castoldi
Abstract  |  Full text  |  PDF 171
Detection of secondary genetic aberrations in follicle center cell derived lymphomas: assessment of the reliability of comparative genomic hybridization and standard chromosome analysis FREE
A Viardot, J I Martin-Subero, R Siebert, S Harder, S Gesk, M Bentz & B Schlegelberger
Abstract  |  Full text  |  PDF 177
Correspondence
The natural history and clinico-pathological features of the variant form of hairy cell leukemia FREE
E Matutes, A Wotherspoon, V Brito-Babapulle & D Catovsky
Abstract  |  Full text  |  PDF 184
Severe thrombocytopenia and clinical bleeding associated with rituximab infusion in a lymphoma patient with massive splenomegaly without leukemic invasion FREE
C Rigamonti, C Volta, S Colombi, L Forti, F Savinelli, G Gaidano & E Bartoli
Abstract  |  Full text  |  PDF 186
Remission of severe cold agglutinin disease Rituximab therapy FREE
N Layios, E Van Den Neste, E Jost, V Deneys, J M Scheiff & A Ferrant
Abstract  |  Full text  |  PDF 187
Age cohort subgroups in adult acute myeloid leukaemia studies - the population perspective FREE
S J Proctor & P R A Taylor
Abstract  |  Full text  |  PDF 188
CD13/aminopeptidase N involvement in dendritic cell maturation FREE
V H J van der Velden, P J M Leenen & H A Drexhage
Abstract  |  Full text  |  PDF 190
Deletion of the multidrug resistance protein 1 (MRP1) gene in acute myeloid leukemia patients with inversion 16: expression of MRP1 homologues FREE
D M van der Kolk, E G E de Vries & E Vellenga
Abstract  |  Full text  |  PDF 191
Is HLA-DR4 or the HLA-DRB1*0402 allele associated with decreased risk for CML? FREE
G Pawelec & W Wagner
Abstract  |  Full text  |  PDF 192
January 2001, Volume 15, Number 1
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