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April 2000, Volume 14, Number 4

Table of Contents

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Editorial
MUM1: a step ahead toward the understanding of lymphoma histogenesis FREE
G Gaidano & A Carbone
Abstract  |  Full text  |  PDF 563
Review
Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia FREE
H L McLeod, E Y Krynetski, M V Relling & W E Evans
Abstract  |  Full text  |  PDF 567
Original Manuscripts
Fludarabine: an effective treatment in patients with splenic lymphoma with villous lymphocytes FREE
F Lefrère, O Hermine, C Belanger, S François, H Tilly, J-C Lebas de La Cour, F Valensi, B Varet & X Troussard
Abstract  |  Full text  |  PDF 573
Diphtheria toxin fused to human interleukin-3 is toxic to blasts from patients with myeloid leukemias FREE
A E Frankel, J A McCubrey, M S Miller, S Delatte, J Ramage, M Kiser, G L Kucera, R L Alexander, M Beran, E P Tagge, R J Kreitman & D E Hogge
Abstract  |  Full text  |  PDF 576
Methylation status of the p15INK4B gene in hematopoietic progenitors and peripheral blood cells in myelodysplastic syndromes FREE
E Aoki, T Uchida, H Ohashi, H Nagai, T Murase, A Ichikawa, K Yamao, T Hotta, T Kinoshita, H Saito & T Murate
Abstract  |  Full text  |  PDF 586
The interaction between EEN and Abi-1, two MLLfusion partners, and synaptojanin and dynamin: implications for leukaemogenesis FREE
C W So, C K C So, N Cheung, S L Chew, M H Sham & L C Chan
Abstract  |  Full text  |  PDF 594
Sensitisation of HL60 human leukaemic cells to cytotoxic drug-induced apoptosis by inhibition of PI3-kinase survival signals FREE
D M O'Gorman, S L McKenna, A J McGahon, K A Knox & T G Cotter
Abstract  |  Full text  |  PDF 602
Induction of apoptosis in human hematopoietic U937 cells by granulocyte-macrophage colony-stimulating factor: possible existence of caspase 3-like pathway FREE
E Okuma, K Saeki, M Shimura, Y Ishizaka, E Yasugi & A Yuo
Abstract  |  Full text  |  PDF 612
Mechanisms of resistance to apoptosis in human AML blasts: the role of differentiation-induced perturbations of cell-cycle checkpoints FREE
N J Ketley, P D Allen, S M Kelsey & A C Newland
Abstract  |  Full text  |  PDF 620
Characterization of a novel negative regulatory element in the human interleukin 4 promoter FREE
S Georas, J Cumberland, T Burke, E Park, S Ono & V Casolaro
Abstract  |  Full text  |  PDF 629
Cytogenetic analogy between myelodysplastic syndrome and acute myeloid leukemia of elderly patients FREE
G Rossi, A M Pelizzari, D Bellotti, M Tonelli & S Barlati
Abstract  |  Full text  |  PDF 636
Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism FREE
P E Hoyle, P W Moye, L S Steelman, W L Blalock, R A Franklin, M Pearce, H Cherwinski, E Bosch, M McMahon & J A McCubrey
Abstract  |  Full text  |  PDF 642
Identification of a genetic locus modulating splenomegaly induced by granulocyte colony-stimulating factor in mice FREE
A W Roberts, M Hasegawa, D Metcalf & S J Foote
Abstract  |  Full text  |  PDF 657
Biological effects induced by variable levels of BCR-ABL protein in the pluripotent hematopoietic cell line UT-7 FREE
C Issaad, M Ahmed, S Novault, M L Bonnet, T Bennardo, B Varet, W Vainchenker & A G Turhan
Abstract  |  Full text  |  PDF 662
Immunoglobulin kappa gene rearrangements between the kappa deleting element and Jkappa recombination signal sequences in acute lymphoblastic leukemia and normal hematopoiesis FREE
T Seriu, T E Hansen-Hagge, Y Stark & C R Bartram
Abstract  |  Full text  |  PDF 671
Biological characteristics and prognosis of adult acute myeloid leukemia with internal tandem duplications in the Flt3 gene FREE
W J C Rombouts, I Blokland, B Löwenberg & R E Ploemacher
Abstract  |  Full text  |  PDF 675
Prognostic factors in infants with acute myeloid leukemia FREE
C-H Pui, S C Raimondi, D K Srivastava, X Tong, F G Behm, B Razzouk, J E Rubnitz, J T Sandlund, W E Evans & R Ribeiro
Abstract  |  Full text  |  PDF 684
Regeneration pattern of precursor-B-cells in bone marrow of acute lymphoblastic leukemia patients depends on the type of preceding chemotherapy FREE
E G van Lochem, Y M Wiegers, R van den Beemd, K Hählen, J J M van Dongen & H Hooijkaas
Abstract  |  Full text  |  PDF 688
Expression of a functional inducible nitric oxide synthase in hairy cell leukaemia and ESKOL cell line FREE
V Roman, H Zhao, J-M Fourneau, A Marconi, N Dugas, B Dugas, F Sigaux & J-P Kolb
Abstract  |  Full text  |  PDF 696
P53 mutations in hairy cell leukemia FREE
E A König, W C Kusser, C Day, F Porzsolt, B W Glickman, G Messer, M Schmid, R de Châtel, Z L Marcsek & J Demeter
Abstract  |  Full text  |  PDF 706
Ex vivo assessment of drug response by differential staining cytotoxicity (DiSC) assay suggests a biological basis for equality of chemotherapy irrespective of age for patients with chronic lymphocytic leukaemia FREE
A G Bosanquet & M I Bosanquet
Abstract  |  Full text  |  PDF 712
Evidence against a direct cytotoxic effect of alpha interferon and zidovudine in HTLV-I associated adult T cell leukemia/lymphoma FREE
A Bazarbachi, R Nasr, M E El-Sabban, A Mahé, R Mahieux, A Gessain, N Darwiche, G Dbaibo, J Kersual, Y Zermati, L Dianoux, M K Chelbi-Alix, H de Thé & O Hermine
Abstract  |  Full text  |  PDF 716
The incidence of acute promyelocytic leukemia appears constant over most of a human lifespan, implying only one rate limiting mutation FREE
M Vickers, G Jackson & P Taylor
Abstract  |  Full text  |  PDF 722
Stromal cell-independent differentiation of human cord blood CD34+CD38- lymphohematopoietic progenitors toward B cell lineage FREE
Y Yoshikawa, F Hirayama, M Kanai, S Nakajo, J Ohkawara, M Fujihara, M Yamaguchi, N Sato, M Kasai, S Sekiguchi & K Ikebuchi
Abstract  |  Full text  |  PDF 727
The expansion of murine bone marrow cells preincubated in hypoxia as an in vitro indicator of their marrow-repopulating ability FREE
M G Cipolleschi, E Rovida, Z Ivanovic, V Praloran, M Olivotto & P Dello Sbarba
Abstract  |  Full text  |  PDF 735
Long-term follow-up of advanced-stage low-grade lymphoma patients treated upfront with high-dose sequential chemotherapy and autograft FREE
C Tarella, D Caracciolo, P Corradini, F Zallio, M Ladetto, A Cuttica, G Rossi, D Novero, P Gavarotti & A Pileri
Abstract  |  Full text  |  PDF 740
Variation in the frequency of Epstein-Barr virus-associated Hodgkin's disease with age FREE
K J Flavell, J P Biddulph, C M Constandinou, D Lowe, K Scott, J Crocker, L S Young & P G Murray
Abstract  |  Full text  |  PDF 748
A real-time PCR assay for the quantification of residual malignant cells in B cell chronic lymphatic leukemia FREE
T Pfitzner, A Engert, H Wittor, T Schinköthe, F Oberhäuser, H Schulz, V Diehl & S Barth
Abstract  |  Full text  |  PDF 754
Correspondence
Digoxigenin-end labeled oligonucleotides facilitate the detection of minimal residual disease in acute lymphoblastic leukemia FREE
M Nakao, J W G Janssen, M Schäfer & C R Bartram
Abstract  |  Full text  |  PDF 767
Leukaemic expression of anaplastic large cell lymphoma with 46,XX,ins(2;5)(p23;q15q35) in a child with dihydropyrimidine dehydrogenase deficiency FREE
H van den Berg, A Noorduyn, A B P van Kuilenburg, W Kroes & D de Jong
Abstract  |  Full text  |  PDF 769
Discordant expression of AC133 and AC141 in patients with myelodysplastic syndrome (MDS) and acute myelogeneous leukemia (AML) FREE
C L Green, M Loken, D Buck & H J Deeg
Abstract  |  Full text  |  PDF 770
April 2000, Volume 14, Number 4
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