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May 1998, Volume 12, Number 5

Table of Contents

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Review
Role of the adapter protein CRKL in signal transduction of normal hematopoietic and BCR/ABL-transformed cells FREE
M Sattler & R Salgia
Abstract  |  PDF 637
Original manuscripts: therapy and therapeutic interventions
Down's syndrome in childhood acute lymphoblastic leukemia: clinical characteristics and treatment outcome in four consecutive BFM trials FREE
M Dördelmann, M Schrappe, A Reiter, M Zimmermann, N Graf, G Schott, F Lampert, J Harbott, C Niemeyer, J Ritter, W Dörffel, G Neler, J Kühl & H Riehm for the BFM Group
Abstract  |  PDF 645
The role of intensive AML-specific therapy in treatment of children with RAEB and RAEB-t FREE
U Creutzig, C Bender-Götze, J Ritter, M Zimmermann, B Stollmann-Gibbels, D Körholz & C Niemeyer
Abstract  |  PDF 652
Hypersensitivity reactions to L-asparaginase do not impact on the remission duration of adults with acute lymphoblastic leukemia FREE
R A Larson, M H Fretzin, R K Dodge & C A Schiffer
Abstract  |  PDF 660
Acute lymphoblastic leukemia
Multilineage involvement of Philadelphia chromosome positive acute lymphoblastic leukemia FREE
T M Schenk, A Keyhani, S Bottcher, K-O Kliche, A Goodacre, J-Q Guo, R B Arlinghaus, H M Kantarjian & M Andreeff
Abstract  |  PDF 666
Acute lymphoblastic leukemia
Minimal residual disease after intensive induction therapy in childhood acute lymphoblastic leukemia predicts outcome FREE
B Gruhn, S Hongeng, H Yi, M L Hancock, J E Rubnitz, G A M Neale & G R Kitchingman
Abstract  |  PDF 675
Apoptosis
IL-3 withdrawal activates a CrmA-insensitive poly(ADP-ribose) polymerase cleavage enzyme in factor-dependent myeloid progenitor cells FREE
K Antoku, Z Liu & D E Johnson
Abstract  |  PDF 682
Transcription factors
The myeloid zinc finger gene (MZF-1) delays retinoic acid-induced apoptosis and differentiation in myeloid leukemia cells FREE
K A Robertson, D P Hill, M R Kelley, R Tritt, B Crum, S Van Epps, E Srour, S Rice & R Hromas
Abstract  |  PDF 690
Growth factors: cytokines and cell signaling
Unconventional rapid ERK1,2 activation is indispensable for proliferation of the growth factor-independent myeloid leukemic cell line KG1 FREE
R M Y Barge, J Dorrestijn, J H F Falkenburg, R Willemze & J A Maassen
Abstract  |  PDF 699
Molecular cytogenetics
A FISH cosmid 'cocktail' for detection of 13q deletions in chronic lymphocytic leukaemia - comparison with cytogenetics and Southern hybridization FREE
M Merup, M Jansson, M Corcoran, Y Liu, X Wu, O Rasool, B Stellan, M Hermansson, G Juliusson, G Gahrton & S Einhorn
Abstract  |  PDF 705
Immunobiology and immunotherapy
In vivo targeting of leukemic cells using diphtheria toxin fused to murine GM-CSF FREE
H Rozemuller, E J C Rombouts, I P Touw, D J P FitzGerald, R J Kreitman, A Hagenbeek & A C M Martens
Abstract  |  PDF 710
Normal hemopoiesis and stemcellology
Differential growth factor requirement of primitive cord blood hematopoietic stem cell for self-renewal and amplification vs proliferation and differentiation FREE
W Piacibello, F Sanavio, L Garetto, A Severino, A Dané, L Gammaitoni & M Aglietta
Abstract  |  PDF 718
Normal hemopoiesis and stemcellology
Human cord blood-derived primitive progenitors are enriched in CD34+c-kit- cells: correlation between long-term culture-initiating cells and telomerase expression FREE
H Sakabe, N Yahata, T Kimura, Z Z Zeng, H Minamiguchi, H Kaneko, K J Mori, K Ohyashiki, J H Ohyashiki, K Toyama, T Abe & Y Sonoda
Abstract  |  PDF 728
Normal hemopoiesis and stemcellology
Stromal factors support the expansion of the whole hemopoietic spectrum from bone marrow CD34+DR- cells and of some hemopoietic subsets from CD34+ and CD34+DR+ cells FREE
Ph Herman, A Ferrant, M De Bruyère & N Straetmans
Abstract  |  PDF 735
Peripheral blood progenitors auto-transplantation
Collection of Philadelphia-negative peripheral blood progenitor cells in unselected patients with chronic granulocytic leukaemia FREE
A L Lennard, N Storey, A M Dickinson, J A Irving, D Rowe, J S Conn & S J Proctor on behalf of the Northern Regional Haematology Group
Abstract  |  PDF 746
Lymphoma
Most of CD30+ anaplastic large cell lymphoma of B cell type show a somatic mutation in the IgH V region genes FREE
T Kuze, N Nakamura, Y Hashimoto & M Abe
Abstract  |  PDF 753
Biotechnical methods section (BTS)
A new fingerprint method for sequence analysis of chromosomal translocations at the genomic DNA level FREE
T Leis, R Repp, A Borkhardt, M Metzler, F Schläger, J Harbott & F Lampert
Abstract  |  PDF 758
Culture system for extensive production of CD19+IgM+ cells by human cord blood CD34+ progenitors FREE
J-I Ohkawara, K Ikebuchi, M Fujihara, N Sato, F Hirayama, M Yamaguchi, K J Mori & S Sekiguchi
Abstract  |  PDF 764
Correspondence
Detection of Epstein-Barr virus DNA in serum of transplanted patients: a new diagnostic guide for lymphoproliferative diseases FREE
J Fontan, A Bassignot, C Mougin, J Y Cahn & M Lab
Abstract  |  PDF 772
Tetraspan transmembrane antigen levels in Burkitt lymphoma cell lines FREE
M Ferrer, M Yunta & P A Lazo
Abstract  |  PDF 773
Highly efficient and non-toxic DNA isolation from very old bone marrow smears FREE
B Anderegg, S Schlüter & H Kabisch
Abstract  |  PDF 774
European union concerted action workshop on 11q23
General Report on the European Union Concerted Action Workshop on 11q23, London, UK, May 1997 FREE
L M Secker-Walker on behalf of the European 11q23 Workshop participants
Abstract  |  PDF 776
European union concerted action workshop on 11q23
Hematologic malignancies with t(4;11)(q21;q23) - a cytogenetic, morphologic, immunophenotypic and clinical study of 183 cases FREE
B Johansson, A V Moorman, O A Haas, A E Watmore, K L Cheung, S Swanton & L M Secker-Walker
Abstract  |  PDF 779
European union concerted action workshop on 11q23
The t(6;11)(q27;q23) translocation in acute leukemia: a laboratory and clinical study of 30 cases FREE
M Martineau, R Berger, D M Lillington, A V Moorman & L M Secker-Walker
Abstract  |  PDF 788
European union concerted action workshop on 11q23
Hematological malignancies with t(9;11)(p21-22;q23) - a laboratory and clinical study of 125 cases FREE
G J Swansbury, R Slater, B J Bain, A V Moorman & L M Secker-Walker
Abstract  |  PDF 792
European union concerted action workshop on 11q23
The t(10;11)(p12;q23) translocation in acute leukaemia: a cytogenetic and clinical study of 20 patients FREE
D M Lillington, B D Young, R Berger, M Martineau, A V Moorman & L M Secker-Walker
Abstract  |  PDF 801
European union concerted action workshop on 11q23
The translocations, t(11;19)(q23;p13.1) and t(11;19)(q23;p13.3): a cytogenetic and clinical profile of 53 patients FREE
A V Moorman, A Hagemeijer, C Charrin, H Rieder & L M Secker-Walker
Abstract  |  PDF 805
European union concerted action workshop on 11q23
Ten novel 11q23 chromosomal partner sites FREE
C J Harrison, A Cuneo, R Clark, B Johansson, M Lafage-Pochitaloff, F Mugneret, A V Moorman & L M Secker-Walker
Abstract  |  PDF 811
European union concerted action workshop on 11q23
Hematological malignancies with a deletion of 11q23: cytogenetic and clinical aspects FREE
J Harbott, M Mancini, Ch Verellen-Dumoulin, A V Moorman & L M Secker-Walker
Abstract  |  PDF 823
European union concerted action workshop on 11q23
Derivative chromosomes of 11q23-translocations in hematologic malignancies FREE
B Johansson, A V Moorman & L M Secker-Walker
Abstract  |  PDF 828
European union concerted action workshop on 11q23
Myelodysplastic syndromes associated with 11q23 abnormalities FREE
B J Bain, A V Moorman, B Johansson, A B Mehta & L M Secker-Walker
Abstract  |  PDF 834
European union concerted action workshop on 11q23
Secondary acute leukemia and myelodysplastic syndrome with 11q23 abnormalities FREE
L M Secker-Walker, A V Moorman, B J Bain & A B Mehta
Abstract  |  PDF 840
May 1998, Volume 12, Number 5
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