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April 1997, Volume 11, Number 4

Table of Contents

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Reviews
Mechanisms of apoptotic cell death FREE
S Rowan & D E Fisher
Abstract  |  PDF 457
Functional features of neutrophils induced by G-CSF and GM-CSF treatment: differential effects and clinical implications FREE
K Spiekermann, J Roesler, A Emmendoerffer, J Elsner & K Welte
Abstract  |  PDF 466
Original manuscripts: leading article
Constitutive activation of mitogen-activated protein kinase pathway in acute leukemia cells FREE
M Towatari, H Iida, M Tanimoto, H Iwata, M Hamaguchi & H Saito
Abstract  |  PDF 479
Therapy and therapeutic interventions
A randomized trial of high- vs standard-dose mitoxantrone with cytarabine in elderly patients with acute myeloid leukemia FREE
E J Feldman, K Seiter, L Damon, C Linker, H Rugo, C Ries, DC Case Jr, M Beer & T Ahmed
Abstract  |  PDF 485
Molecular biology
Topoisomerase II inhibitors induce DNA double-strand breaks at a specific site within the AML1 locus FREE
M Stanulla, J Wang, D S Chervinsky & P D Aplan
Abstract  |  PDF 490
Molecular biology
Antisense src expression inhibits tyrosine phosphorylation of Shc and its association with Grb2 and Sos which leads to MAP kinase activation in U937 human leukemia cells FREE
M Yamaguchi, T Tanaka, M Waki, A Kitanaka, H Kamano, Y Kubota, H Ohnishi, J Takahara & S Irino
Abstract  |  PDF 497
Tumor suppressor genes: signal transduction and cell
Effects of antisense p21 (WAF1/CIP1/MDA6) expression on the induction of differentiation and drug-mediated apoptosis in human myeloid leukemia cells (HL-60) FREE
A J Freemerman, J A Vrana, R M Tombes, H Jiang, S P Chellappan, P B Fisher & S Grant
Abstract  |  PDF 504
Molecular cytogenetics
Variant complex translocations involving chromosomes 1, 9, 9, 15 and 17 in acute promyelocytic leukemia without RARalpha/PML gene fusion rearrangement FREE
S K Gogineni, H O Shah, M Chester, J H Lin, M Garrison, A Alidina, E Bayani & R S Verma
Abstract  |  PDF 514
Molecular cytogenetics
Mosaicism of the 5q deletion as assessed by interphase FISH is a common phenomenon in MDS and restricted to myeloid cells FREE
M J P L Kroef, M J W Bolk, P Muus, J W Wessels, G C Beverstock, R Willemze & J E Landegent
Abstract  |  PDF 519
Growth factors and cytokines
Thrombopoietin augments ex vivo expansion of human cord blood-derived hematopoietic progenitors in combination with stem cell factor and flt3 ligand FREE
Y Ohmizono, H Sakabe, T Kimura, S Tanimukai, T Matsumura, H Miyazaki, S D Lyman & Y Sonoda
Abstract  |  PDF 524
Growth factors and cytokines
Megakaryocyte growth and development factor (MGDF)-induced acute leukemia cell proliferation and clonal growth is associated with functional c-mpl FREE
W Piacibello, F Sanavio, M F Brizzi, L Garetto, A Severino, M G Aronica, G Dragonetti, M Aglietta & L Pegoraro
Abstract  |  PDF 531
Growth factors and cytokines
Thrombopoietin supports the continuous growth of cytokine-dependent human leukemia cell lines FREE
H G Drexler, M Zaborski & H Quentmeier
Abstract  |  PDF 541
Growth factors and cytokines
Induction of macrophagic differentiation and cytokine secretion by IgG1 molecules in human normal monocytes and myelogenous leukemia cells FREE
A Micouin, D Rouillard & B Bauvois
Abstract  |  PDF 552
Sensitivity and resistance to leukemia
Differential effect of GM-CSF pretreatment on intracellular Ara-C metabolism in normal bone marrow mononuclear cells vs acute myeloid leukemia (AML) blasts FREE
C Reuter, E Schleyer, C Rolf, B Wörmann, T Büchner & W Hiddemann
Abstract  |  PDF 561
Immunobiology
CD40 triggering of chronic lymphocytic leukemia B cells results in efficient alloantigen presentation and cytotoxic T lymphocyte induction by up-regulation of CD80 and CD86 costimulatory molecules FREE
L E Van den Hove, S W Van Gool, P Vandenberghe, M Bakkus, K Thielemans, M A Boogaerts & J L Ceuppens
Abstract  |  PDF 572
Stem cell biology
Peripheral blood is a source of BCR-ABL-negative pre-progenitors in early chronic phase chronic myeloid leukemia FREE
I D Lewis, D N Haylock, S Moore, L B To & T P Hughes
Abstract  |  PDF 581
Epidemiology
Socioeconomic factors in the families of children with lymphoid malignancy in the UAE FREE
T Révész, C Mpofu, C Oyejide & A Bener
Abstract  |  PDF 588
Lymphoma
Expression of LAZ3/BCL6 in follicular center (FC) B cells of reactive lymph nodes and FC-derived non-Hodgkin lymphomas FREE
S Bajalica-Lagercrantz, F Piehl, J Lagercrantz, J Lindahl, G Weber, J P Kerckeart, A Porwit-MacDonald & M Nordenskjöld
Abstract  |  PDF 594
New cell line
Establishment of a novel human acute myeloblastic leukemia cell line (YNH-1) with t(16;21), t(1;16) and 12q13 translocations FREE
K Yamamoto, H Hamaguchi, K Nagata, M Kobayashi, F Tanimoto & M Taniwaki
Abstract  |  PDF 599
Correspondence: special case report
A case of acute eosinophilic granulocytic leukemia with PML-RAR alpha fusion gene expression and response to all-trans retinoic acid FREE
R-Q Yu, W Huang, S-J Chen, S-D Jiang & Z Chen
Abstract  |  PDF 609
Case report
Translocation (2;8)(p12;q24) in blastic transformation of atypical chronic myeloid leukemia FREE
S K Ma, K L Au, T S K Wan & L C Chan
Abstract  |  PDF 612
An extremely delayed cytogenetic response to interferon-alpha in a patient with chronic myeloid leukaemia FREE
A J Whiteway, C D L Reid & N C P Cross
Abstract  |  PDF 614
Letter to the Editor
Association between b3a2 BCR/ABL fusion and chronic myeloid leukemia with thrombocythemia onset: fortuitous or real? FREE
Y L Kwong
Abstract  |  PDF 617
April 1997, Volume 11, Number 4
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