Laboratory Investigation TOP TEN

The top ten charts the articles that have been downloaded most often, in HTML format, from the Laboratory Investigation website in recent weeks. The chart does not rank the quality, scientific significance or citation impact of the content. However, it may bring articles to your attention that you might not have otherwise noticed. We hope you enjoy them.

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October 2009

  1. Connecting the dots: obesity, fatty acids and cancer

    Philip A Wood

    doi:10.1038/labinvest.2009.99

  2. Neutrophils: Molecules, Functions and Pathophysiological Aspects FREE

    Véronique Witko-Sarsat, Philippe Rieu, Béatrice Descamps-Latscha, Philippe Lesavre and Lise Halbwachs-Mecarelli

    doi:10.1038/labinvest.3780067

  3. Estrogen treatment decreases matrix metalloproteinase (MMP)-9 in autoimmune demyelinating disease through estrogen receptor alpha (ERalpha)

    Stefan M Gold, Manda V Sasidhar, Laurie B Morales, Sienmi Du, Nancy L Sicotte, Seema K Tiwari-Woodruff and Rhonda R Voskuhl

    doi:10.1038/labinvest.2009.79

  4. Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma FREE

    Wendy Anne Boivin, Dawn Michelle Cooper, Paul Ryan Hiebert and David James Granville

    doi:10.1038/labinvest.2009.91

  5. Paracrine induction of endothelium by tumor exosomes FREE

    Joshua L Hood, Hua Pan, Gregory M Lanza and Samuel A Wickline

    doi:10.1038/labinvest.2009.94

  6. Free fatty acids enhance breast cancer cell migration through plasminogen activator inhibitor-1 and SMAD4

    Chang Hyun Byon, Robert W Hardy, Changchun Ren, Selvarangan Ponnazhagan, Danny R Welch, Jay M McDonald and Yabing Chen

    doi:10.1038/labinvest.2009.97

  7. Overexpression of endoplasmic reticulum protein 29 regulates mesenchymal–epithelial transition and suppresses xenograft tumor growth of invasive breast cancer cells FREE

    I Fon Bambang, Songci Xu, Jianbiao Zhou, Manuel Salto-Tellez, Sunil K Sethi and Daohai Zhang

    doi:10.1038/labinvest.2009.87

  8. Community-acquired methicillin-resistant Staphylococcus aureus: the role of Panton–Valentine leukocidin FREE

    Susan Boyle-Vavra and Robert S Daum

    doi:10.1038/labinvest.3700501

  9. Bortezomib-mediated expression of p27Kip1 through S-phase kinase protein 2 degradation in epithelial ovarian cancer

    Shahab Uddin, Maqbool Ahmed, Azhar R Hussain, Zeenath Jehan, Fouad Al-Dayel, Adnan Munkarah, Prashant Bavi and Khawla S Al-Kuraya

    doi:10.1038/labinvest.2009.75

  10. Mechanisms of parenchymal injury and signaling pathways in ectatic ducts of chronic pancreatitis: implications for pancreatic carcinogenesis FREE

    Umesh K Bhanot and Peter Möller

    doi:10.1038/labinvest.2009.19

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