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Cervical cancer is a major public health problem, and cervical cytology screening requires considerable human effort to screen the millions of pap smears taken each year. Infrared spectroscopy offers an alternative to conventional cytology, whereby infrared micro-spectroscopy can be performed on conventional cytological preparations and coupled with sophisticated data analysis to determine whether or not a cytological sample is abnormal. The cover is an artistic interpretation related to the proof-of-concept paper by Schubert et al. on page 1068–1077.