TABLE OF CONTENTS

Volume 89, Issue 5 (May 2009)

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Pathobiology in Focus

Mechanisms of parenchymal injury and signaling pathways in ectatic ducts of chronic pancreatitis: implications for pancreatic carcinogenesis FREE

Umesh K Bhanot and Peter Möller

89: 489-497; advance online publication, March 23, 2009; doi:10.1038/labinvest.2009.19

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Research Articles

Indoleamine 2,3-dioxygenase overexpression causes kynurenine-modification of proteins, fiber cell apoptosis and cataract formation in the mouse lens

Maneesh Mailankot, Magdalena M Staniszewska, Heather Butler, Moonkyung H Caprara, Scott Howell, Benlian Wang, Catherine Doller, Lixing W Reneker and Ram H Nagaraj

89: 498-512; advance online publication, March 23, 2009; doi:10.1038/labinvest.2009.22

Tenofovir renal toxicity targets mitochondria of renal proximal tubules

James J Kohler, Seyed H Hosseini, Amy Hoying-Brandt, Elgin Green, David M Johnson, Rodney Russ, Dung Tran, C Michael Raper, Robert Santoianni and William Lewis

89: 513-519; advance online publication, March 9, 2009; doi:10.1038/labinvest.2009.14

Interstitial fibrosis and microvascular disease of the heart in uremia: amelioration by a calcimimetic

Nadezda Koleganova, Grzegorz Piecha, Eberhard Ritz, Raffi Bekeredjian, Peter Schirmacher, Claus Peter Schmitt and Marie-Luise Gross

89: 520-530; advance online publication, February 2, 2009; doi:10.1038/labinvest.2009.7

NGAL decreases E-cadherin-mediated cell–cell adhesion and increases cell motility and invasion through Rac1 in colon carcinoma cells

Limei Hu, Walter Hittelman, Tao Lu, Ping Ji, Ralph Arlinghaus, Ilya Shmulevich, Stanley R Hamilton and Wei Zhang

89: 531-548; advance online publication, March 23, 2009; doi:10.1038/labinvest.2009.17

Sepsis induces extensive autophagic vacuolization in hepatocytes: a clinical and laboratory-based study

Eizo Watanabe, Jared T Muenzer, William G Hawkins, Christopher G Davis, David J Dixon, Jonathan E McDunn, Daniel J Brackett, Megan R Lerner, Paul E Swanson and Richard S Hotchkiss

89: 549-561; advance online publication, February 2, 2009; doi:10.1038/labinvest.2009.8

Expression of stem cell factor and its receptor c-Kit during the development of intrahepatic cholangiocarcinoma

Tümen Mansuroglu, Pierluigi Ramadori, József Dudás, Ihtzaz Malik, Kristoff Hammerich, László Füzesi and Giuliano Ramadori

89: 562-574; advance online publication, March 2, 2009; doi:10.1038/labinvest.2009.15

Hypoxia influences linearly patterned programmed cell necrosis and tumor blood supply patterns formation in melanoma

Shiwu Zhang, Man Li, Danfang Zhang, Shaoyan Xu, Xiaoyu Wang, Zhiyong Liu, Xiulan Zhao and Baocun Sun

89: 575-586; advance online publication, March 16, 2009; doi:10.1038/labinvest.2009.20

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Technical Reports

Increased expression of metastasis-related genes in hypoxic cells sorted from cervical and lymph nodal xenograft tumors

Naz Chaudary and Richard P Hill

89: 587-596; advance online publication, March 23, 2009; doi:10.1038/labinvest.2009.16

Robust global micro-RNA profiling with formalin-fixed paraffin-embedded breast cancer tissues

Angela B Y Hui, Wei Shi, Paul C Boutros, Naomi Miller, Melania Pintilie, Tony Fyles, David McCready, Derek Wong, Kate Gerster, Igor Jurisica, Linda Z Penn and Fei-Fei Liu

89: 597-606; advance online publication, March 16, 2009; doi:10.1038/labinvest.2009.12

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Corrigendum

PPAR-bold italic gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta  FREE

Toru Kawai, Takao Masaki, Shigehiro Doi, Tetsuji Arakawa, Yukio Yokoyama, Toshiki Doi, Nobuoki Kohno and Noriaki Yorioka

89: 607; doi:10.1038/labinvest.2008.156

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