Laboratory Investigation

TABLE 2

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Reduced acetaminophen-induced liver injury in mice by genetic disruption of IL-1 receptor antagonist

Takuya Ishibe, Akihiko Kimura, Yuko Ishida, Tatsunori Takayasu, Takahito Hayashi, Koichi Tsuneyama, Kouji Matsushima, Ikuhiro Sakata, Naofumi Mukaida and Toshikazu Kondo

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Table 2. Intrahepatic protein contents of IL-1alpha, IL-1bold italic beta, and IL-1ra in unchallenged WT and IL-1ra KO mice

Figure and tables index
CytokinesWTIL-1ra KO
IL-alpha 35.1plusminus10.845.4plusminus10.4
IL-1beta 5.03plusminus0.667.12plusminus0.12
IL-1ra54.5plusminus19.5Not detected

 IL, interleukin; IL-1ra, IL-1 receptor antagonist; KO, knockout; WT, wild type.

 The data were expressed as pg/mg total protein for each sample.

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