Laboratory Investigation

FIGURE 3

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Regulation of scar formation by vascular endothelial growth factor

Traci A Wilgus, Ahalia M Ferreira, Tatiana M Oberyszyn, Valerie K Bergdall and Luisa A DiPietro

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Figure 3.

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Effect of VEGF on fetal wound healing. Masson's trichrome staining was used to identify scar tissue in E15 fetal wounds at 10 days post-wounding. Representative trichrome-stained wound sections are shown to illustrate the lack of scarring in wounds injected PBS (a, b) and the presence of a scar in wounds injected with 0.1 mug rmVEGF164 (c, d). Arrows indicate the wound bed/scar margins (scale bar=200 mum).

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