Laboratory Investigation

FIGURE 2

FROM:

Angiogenic heterogeneity in head and neck squamous cell carcinoma: biological and therapeutic implications

Rifat Hasina, Mark E Whipple, Leslie E Martin, Winston Patrick Kuo, Lucila Ohno-Machado and Mark W Lingen

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Figure 2.

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Principal component analysis (PCA) of HNSCC samples using the angiogenesis gene list or the entire gene list. The PCA clustering using the angiogenesis gene list revealed the presence of two major clusters of patient samples along with a third distinct, solitary sample (a). PCA analysis using the entire data set demonstrated less distinct clustering suggesting that the angiogenesis-related genes represented a potential key program for distinguishing between tumors (b).

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