Laboratory Investigation

FIGURE 3

FROM:

RNA expression analysis of formalin-fixed paraffin-embedded tumors

Shannon K Penland, Temitope O Keku, Chad Torrice, Xiaping He, Janakiraman Krishnamurthy, Katherine A Hoadley, John T Woosley, Nancy E Thomas, Charles M Perou, Robert S Sandler and Norman E Sharpless

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Figure 3.

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Unsupervised hierarchical clustering of transcripts that passed pre-defined criteria from informative expression profiles of FFPE and frozen tumors. Data are median-centered, green represents expression below median, red represents above median and gray represents missing data. Three representative clusters are indicated by colored bars and explicitly shown on the right. Genes names in these clusters are colored if they typify the indicated tumor type as demonstrated by greater than median expression in the majority of tumors of the indicated histology in one of two publicly available data sets20, 26 (orange, colon cancer; blue, melanoma; purple, breast).

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