TABLE 1

FROM:

Reversibility of experimental rabbit liver cirrhosis by portal collagenase administration

Bo Jin, Harvey J Alter, Zhi-Cheng Zhang, J Wai-Kuo Shih, Juan M Esteban, Tao Sun, Yun-Sheng Yang, Qi Qiu, Xiao-Lin Liu, Lin Yao, Hai-Dong Wang and Liu-Fang Cheng

Table 1. Blood tests for safety evaluation

Test	Rabbit with 2 mg collagenase portal perfusion (n=1)		Rabbit with 4 mg collagenase portal perfusion (n=1)		Rabbit with 6 mg collagenase portal perfusion (n=1)
	Preperfusion	Postperfusion	Preperfusion	Postperfusion	Preperfusion	Postperfusion
White blood cells (109/l)	9.5	7.6	9.2	5.3	4.4	7.1
Erythrocytes (1012/l)	4.17	4.02	6.18	5.68	5.15	5.33
Hemoglobin (g/dl)	9.4	9.0	12.2	11.3	10.8	11.2
Platelets (109/l)	46	200	292	419	106	101
ALT (IU/l)	30	28	34	34	29	27
AST (IU/l)	114	54	46	18	33	24
Bilirubin (mol/l)	0.7	2.6	3.3	1.3	1.6	1.5
Albumin (g/l)	15	14	17	17	18	17
Urea (mmol/l)	10.3	8.0	7.2	6.9	5.2	7.4
Creatine (mol/l)	139	91	73	72	77	94