Laboratory Investigation

TABLE 2

FROM:

Molecular characterization of salivary gland malignancy using the Smgb-Tag transgenic mouse model

Antti A Mäkitie, Patricia Pintor dos Reis, Shilpi Arora, Christina MacMillan, Giles C Warner, Mahadeo Sukhai, Irving Dardick, Bayardo Perez-Ordonez, Richard Wells, Dale Brown, Ralph Gilbert, Jeremy Freeman, Patrick Gullane, Jonathan Irish and Suzanne Kamel-Reid

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Table 2. Function and mapping information of the five genes selected for validation

Unigene ID Gene symbol/name Mouse chromosome Human chromosome Function
Mm. 9537Lcn2/lipocalin 22B9q34Binding/transport of small hydrophobic molecules
     
Mm. 3063Ptn/pleiotrophin6B17q33–q34Growth-associated protein, signalling molecule with putative role in apoptosis and bone formation
     
Mm. 6417Cd24a/Cd24a antigen10B26q21Cell surface antigen/defense response
     
Mm. 1951Rnps1/ribonucleic acid binding protein S117A3.316p13.3Nucleic acid binding protein/may play a role in regulation of splicing and transcription
     
Mm. 18856Mapk6/mitogen-activated protein kinase 69D15q21Protein kinase, plays a role in signalling regulating cell division
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