Laboratory Investigation

FIGURE 3

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Infiltration of CD8+ T cells containing RANTES/CCL5+ cytoplasmic granules in actively inflammatory lesions of human chronic gastritis

Noriko Ohtani, Haruo Ohtani, Takashi Nakayama, Hiroshi Naganuma, Eiichi Sato, Toshio Imai, Hiroshi Nagura and Osamu Yoshie

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Figure 3.

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Quantitative analyses of chemokine receptor-positive cells in chronic gastritis. Vertical axis represents number of immunoreactive cells per 0.19 mm2, the whole area of a times 400 field. All figures are expressed by Box–Whisker plot showing 75-, median-, and 25-percentile values. (a) Comparison among CCR5+, CXCR3+, and CCR4+ mononuclear cells. (b) Correlation between the number of CCR5+ cells and the degree of neutrophil infiltration. The numbers of areas showing neutrophil infiltration of 0, 1+, 2+, and 3+ were 12, 23, 4, and 0, respectively. (c) Difference of the number of CCR5+ cells between corpus and antrum. (d) Correlation between the number of CCR5+ cells and the degree of intestinal metaplasia. Correlation analyzed by Spearman's test (b, d).

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