Laboratory Investigation

FIGURE 3

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Mice depleted of CD8+ T and NK cells are resistant to injury caused by cecal ligation and puncture

Edward R Sherwood, Victor T Enoh, Erle D Murphey and Cheng Y Lin

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Figure 3.

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Rectal temperature and arterial blood gases were analyzed at 16 h after CLP in wild-type and CD8 knockout (CD8KO) mice treated with nonspecific IgG or anti-asialoGM1 (alphaAsGM1). Sham wild-type mice served as control. *Significantly (P<0.05) different from sham. nablaSignificantly (P<0.05) different from wild-type mice treated with nonspecific IgG. Values represent the meanplusminuss.e.m. n=5–7 mice/group.

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