Laboratory Investigation

FIGURE 1

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Mice depleted of CD8+ T and NK cells are resistant to injury caused by cecal ligation and puncture

Edward R Sherwood, Victor T Enoh, Erle D Murphey and Cheng Y Lin

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Figure 1.

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Wild-type mice treated with nonspecific IgG (wild type), beta2 microglobulin knockout mice treated with anti-asialoGM1 (beta2MKO/alphaAsGM1), CD8alpha knockout mice treated with anti-asialoGM1 (CD8KO/alphaAsGM1) and wild-type mice treated with anti-CD8alpha and asialoGM1 (alphaCD8/alphaAsGM1) underwent CLP. Survival was monitored every 12 h. n=8–12 mice/group.

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