Laboratory Investigation

TABLE 2

FROM:

Detection and identification of Variola virus in fixed human tissue after prolonged archival storage

Randal J Schoepp, Michelle D Morin, Mark J Martinez, David A Kulesh, Lisa Hensley, Thomas W Geisbert, Daniel R Brady and Peter B Jahrling

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Table 2. TaqMan® analysis of human tissue presumed to be infected with Variola virus and stored in fixative for a prolonged period of time

Figure and tables index
Sample Species Tissue Agent Orthopoxvirus assay Variola assay
990107-25NHPa LiverNegativeNot detectedb Not detected
211124-11NHPLiver Variola PresentPresent
      
211163-28NHPSkinNegativeNot detectedNot detected
      
211128-48NHPSkin Variola PresentPresent
211128-55NHPSkin Variola PresentPresent
211128-56NHPSkin Variola PresentPresent
211128-60NHPSkin Variola PresentNot detected
211128-61NHPSkin Variola Not detectedNot detected
      
961707HumanLiverNegativeNot detectedNot detected
      
211861-09 Human Skin Unknown Present Not detected
211861-10 Human Skin Unknown Not detected Not detected
211861-11 Human Skin Unknown Present Present
211861-12 Human Skin Unknown Present Not detected

a NHP=nonhuman primate.

b RAPID Detector software designations: present=positive; not detected=negative.

 Italic entries indicate the experimental samples from the numerous controls.

Figure and tables index
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