Laboratory Investigation

FIGURE 8

FROM:

Analysis of the Lung Pathology and Alveolar Macrophage Function in the Acid Sphingomyelinase–Deficient Mouse Model of Niemann-Pick Disease

Rajwinder Dhami, Xingxuan He, Ronald E Gordon and Edward H Schuchman

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Figure 8.

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Superoxide production with phorbol myristate acetate (PMA) stimulation by alveolar cells obtained by BAL from (+/+) and (-/-) ASMKO mice. Mature (approximately 28-week-old) (-/-) mice have almost 2-fold lower superoxide production compared with age-matched normal mice. Values are shown as mean plusminus standard deviation, n = 5 mice per group.

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