Laboratory Investigation

TABLE 3

FROM:

Increased Expression of FGF-8 Isoforms and FGF Receptors in Human Premalignant Prostatic Intraepithelial Neoplasia Lesions and Prostate Cancer

Eeva M Valve, Marja T Nevalainen, Martti J Nurmi, Matti K Laato, Paula M Martikainen and Pirkko L Härkönen

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Table 3. Summary of the Results of Immunohistochemical Stainings for FGF-8 and FGFR1 and FGFR2 in Prostates from Cystoprostatectomies

Prostates from cystoprostatectomiesFGF-8FGFR1FGFR2
 NormalPINNormalPINNormalPIN
P25000/+++0/+++
P260/++/++0/+++0/+++
P400/++/++++++++/++
P440/+-++-+-
P450-0/+-0/+-
P630+0/++/++0/++/++
P930/+++/++++0/++

 PIN, prostatic intraepithelial neoplasia; -, no PIN lesions in the sample.

 Intensity of immunoreactivity: 0, none; +, weak, ++, moderate; +++, strong; 0/+, 0/++, 0/+++, +/++, +/+++, ++/+++: heterogenous distribution of immunoreactivity.

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