Laboratory Investigation

FIGURE 9

FROM:

Monoclonal Light Chain–Mesangial Cell Interactions: Early Signaling Events and Subsequent Pathologic Effects

William J Russell, James Cardelli, Edward Harris, R John Baier and Guillermo A Herrera

BACK TO ARTICLE

Figure 9.

Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

Ki-67 staining of MC with (right panel) and without (left panel) preincubation with anti-c-fos and subsequently incubated with various LC and PDGF-BB as indicated. A and B, Incubated with LCDD-LC; C and D, incubated with PDGF-BB; E and F, incubated with AL-LC; and G and H, incubated with T-LC. Note, by comparing A, B, C, and D (LCDD- and PDGF-BB-treated cells), that c-fos preincubation reduced by approximately half the number of Ki-67 positive cells. The difference between E and F (AL-LC) is not as noticeable. In contrast, the number of Ki-67–positive cells is rather small in G and H, corresponding to MC treated with T-LC. Original magnification, times 160.

BACK TO ARTICLE