TABLE 1

FROM:

Amyloid and Nonfibrillar Deposits in Mice Transgenic for Wild-Type Human Transthyretin: A Possible Model for Senile Systemic Amyloidosis

Mei-hui Teng, Jian-yun Yin, Ruben Vidal, Jorge Ghiso, Asok Kumar, Rahmin Rabenou, Alan Shah, Daniel R Jacobson, Clement Tagoe, Gloria Gallo and Joel Buxbaum

Table 1. Mean Serum Levels of Human TTR in Transgenic Mice (mg/dl)

Age (mo)	Males (n)	Females (n)
< 3	127 32 (13)	167 73 (15)
3–6	156 54 (10)	166 69 (6)
6–12	143 23 (14)	118 58 (8)
12–18	127 33 (5)	148 97 (2)
> 18	*77 34 (14)	*125 62 (12)

 TTR, transthyretin.

^* The differences between male and female transgenic animals are only significant after 18 months of age. In that comparison the two-tailed p value (Mann-Whitney) = 0.0148.