Laboratory Investigation

FIGURE 6

FROM:

Amyloid and Nonfibrillar Deposits in Mice Transgenic for Wild-Type Human Transthyretin: A Possible Model for Senile Systemic Amyloidosis

Mei-hui Teng, Jian-yun Yin, Ruben Vidal, Jorge Ghiso, Asok Kumar, Rahmin Rabenou, Alan Shah, Daniel R Jacobson, Clement Tagoe, Gloria Gallo and Joel Buxbaum

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Figure 6.

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A and B, Immunoelectronmicrographs of a glomerulus from the transgenic male shown in Figure 5 A and B, after incubation with anti-TTR antibody and gold probe enhanced with silver, demonstrate gold-labeled fibrillar deposits on the luminal side of the glomerular basement membrane (bm). Original magnification: A, times25,000; B, times50,000.

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