Laboratory Investigation

FIGURE 1

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Docosahexaenoic Acid Deficit Is Not a Major Pathogenic Factor in Peroxisome-Deficient Mice

A Janssen, M Baes, P Gressens, G P Mannaerts, P Declercq and P P Van Veldhoven

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Figure 1.

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GC analysis of long chain fatty acids in brain. Transmethylated fatty acids from the brain phospholipids of a PEX5-/- mouse (a) and of a PEX5+/+ mouse (b) were separated on a BPX70 column. The FID response during 15 and 30 minutes is shown. As described in "Materials and Methods," the temperature at 15 minutes was 181° C and the temperature gradient was 3° C/minute. The numbered peaks correspond to the following compounds: 1, C20:4n-6; 2, C22:6n-3; 3, C26:0; and 4, C24:6n-3. IS represents the internal standard C27:0.

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