Commentary

Kidney International (2007) 72, 909–911. doi:10.1038/sj.ki.5002544

Vitamin D as a novel nontraditional risk factor for mortality in hemodialysis patients: The need for randomized trials

Z Al-Aly1,2,3

  1. 1Division of Nephrology, Saint Louis University, Saint Louis, Missouri, USA
  2. 2Division of Nephrology, Saint Louis Veterans Affairs Medical Center, Saint Louis, Missouri, USA
  3. 3Saint Louis Veterans Affairs Clinical Research and Epidemiology Center, Saint Louis, Missouri, USA

Correspondence: Z Al-Aly, Division of Nephrology, Saint Louis University Hospital, 3635 Vista Avenue, FDT 9N, Saint Louis, Missouri 63110, USA. E-mail: zalaly@slu.edu

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Abstract

Vitamin D has been used in the context of secondary hyperparathyroidism in patients with end-stage renal disease. A wave of recent studies suggests that vitamin D treatment may be associated with decreased mortality risk in these patients. The article by Wolf et al. further supports these studies by identifying vitamin D deficiency as a risk factor for early mortality in incident hemodialysis patients.

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