Original Article

Kidney International (2007) 72, 1023–1028; doi:10.1038/sj.ki.5002443; published online 18 July 2007

Mortality of Canadians treated by peritoneal dialysis in remote locations

M Tonelli1,2,3,4, B Hemmelgarn5,6, B Culleton5,6, S Klarenbach1,3, J S Gill7,8, N Wiebe1 and B Manns3,5,6 for the Alberta Kidney Disease Network

  1. 1Division of Nephrology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
  2. 2Division of Critical Care Medicine, University of Alberta, Edmonton, Alberta, Canada
  3. 3Institute of Health Economics, Edmonton, Alberta, Canada
  4. 4Department of Public Health Sciences, University of Alberta, Edmonton, Alberta, Canada
  5. 5Division of Nephrology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada
  6. 6Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
  7. 7Division of Nephrology, St Paul's Hospital, Vancouver, British Columbia, Canada
  8. 8Division of Nephrology, Tufts-New England Medical Centre, Boston, Massachusetts, USA

Correspondence: M Tonelli, Division of Nephrology and Immunology, University of Alberta, 7-129 Clinical Science Building, 8440 112 Street, Edmonton, Alberta, Canada T6B 2B7. E-mail: mtonelli-admin@ualberta.ca

Received 16 March 2007; Revised 15 May 2007; Accepted 22 May 2007; Published online 18 July 2007.

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Abstract

Patients residing in remote locations may be more likely to initiate peritoneal dialysis when starting renal replacement therapy to avoid relocation. These patients may have reduced access to medical care, however. To examine the hypothesis that patients residing some distance from their nephrologists would be more likely to select peritoneal dialysis but have an increased risk of mortality, we used prospectively collected data in a random sample of 26 775 patients initiating dialysis in Canada between 1990 and 2000. The distance between the patient's residence at dialysis inception and the practice location of their nephrologists was calculated. We used Cox proportional hazard models to determine the adjusted relation between this distance and clinical outcomes over a mean follow-up period of 2.5 years up to 14 years. Remote-dwelling patients were more likely than urban dwellers to commence peritoneal dialysis in distances ranging from 50 to greater than 300 km than those residing within 50 km. The adjusted rates of death and the adjusted hazard ratio among patients initiating peritoneal dialysis was significantly higher in those living further from the nephrologists than those living within 50 km. Further study into the quality of care delivered to remote-dwelling patients on peritoneal dialysis is needed.

Keywords:

peritoneal dialysis, end-stage renal disease, mortality, geography, cohort-study, rural

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