Commentary

Kidney International (2007) 71, 721–723. doi:10.1038/sj.ki.5002170

Urinary tract infections revisited

G Godaly1 and C Svanborg1

1Institute of Laboratory Medicine, Department of Microbiology, Immunology and Glycobiology, Lund University, Lund, Sweden

Correspondence: C Svanborg, Lund University, Department of Microbiology, Immunology and Glycobiology, Sölvegatan 23, 223 62 Lund, Sweden. E-mail: Catharina.Svanborg@med.lu.se

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Abstract

Urinary tract infections (UTIs) remain a significant clinical problem, despite antibiotic treatment and surgical correction of reflux and malformations. Here we propose that novel molecular tools may be applied to modernize and individualize the diagnosis and therapy of UTI. Determinants of bacterial virulence and host resistance are relatively well understood at the molecular level, and technology for their detection is within reach.

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