Kidney International

FIGURE 7

FROM:

Contribution of Src-FAK signaling to the induction of connective tissue growth factor in renal fibroblasts

A Graness, I Cicha and M Goppelt-Struebe

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Figure 7.

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Regulation of CTGF expression by cytoskeletal dynamics. Signaling pathways analyzed in fibroblasts grown in collagen gels are indicated by bold lines. Dotted lines indicate signaling pathways described in the literature as outlined in the discussion. In the cells firmly attached to collagen-coated plates, alterations of F-actin will not lead to clustering and activation of adhesion proteins.

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