Kidney International

FIGURE 2

FROM:

Donor genomics influence graft events: The effect of donor polymorphisms on acute rejection and chronic allograft nephropathy

STEVEN HOFFMANN, JENNY PARK, LYNN M JACOBSON, REBECCA J MUEHRER, DAVID LORENTZEN, DAVID KLEINER, YOLANDA T BECKER, DEBRA A HULLETT, ROSLYN MANNON, ALLAN D KIRK and BRYAN N BECKER

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Figure 2.

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Kaplan-Meier analysis of time to composite endpoint of biopsy-proven chronic allograft nephropathy (CAN) or graft loss. Donor/recipient pairs positive for the IFN-gamma increased production phenotypes (based on presence of T allele) had a significantly greater rate of reaching the composite end point than donor +/recipient -; donor–/recipient +; and donor–/recipient pairs (P = 0.01).

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