TABLE 1

FROM:

Fat malabsorption induced by gastrointestinal lipase inhibitor leads to an increase in urinary oxalate excretion

RENATO RIBEIRO NOGUEIRA FERRAZ, HANS-GÖRAN TISELIUS and ITA PFEFERMAN HEIBERG

Table 1. Urinary parameters mean values at baseline, after diet and diet + orlistat periods

	Groups
Urinary parameters	Control	Soy oil	Sodium oxalate (NaOx)	Sodium oxalate (NaOx) + soy oil
Volume ml
Baseline	11.1 5.0d	17.4 2.9	10.5 3.5d	11.3 1.2d
Diet	11.7 4.9	6.8 1.6a , c	5.4 1.7a , c	5.7 2.2a , c
Diet + orlistat	16.0 5.5	9.1 3.3a , c	5.5 1.5a , c , d	6.5 2.3a , c , d
Oxalate mg/24 hours
Baseline	0.56 0.1	0.49 0.2	0.57 0.2	0.47 0.1
Diet	0.49 0.1	0.87 0.4a , c	1.60 1.3a , c	3.13 0.9a , c , d , e
Diet + orlistat	0.64 0.1a,b	0.80 0.3a , c	2.48 0.80a , b , c , d	3.87 0.7a , c , d , e
Calcium mg/24 hours
Baseline	0.26 0.1d , e	0.49 0.0	0.39 0.1	0.38 0.0c
Diet	0.31 0.1	0.31 0.0a	0.08 0.0a , c , d	0.04 0.0a , c , d , e
Diet + orlistat	0.45 0.1	0.38 0.1a	0.08 0.0a , c , d	0.16 0.0a , c , d
Citrate mg/24 hours
Baseline	10.5 9.9	14.8 4.2	14.4 8.8	14.1 5.3
Diet	13.8 4.0	8.8 2.3a	9.1 7.2	12.7 9.6
Diet + orlistat	17.0 2.9	12.1 4.7c	6.2 5.5a , c , d	10.3 6.3c
Sodium mEq/L
Baseline	0.7 0.3	0.9 0.2	0.6 0.1	0.6 0.1
Diet	0.4 0.1	0.8 0.2c	2.5 1.0a , c , d	2.9 1.7a , c , d
Diet + orlistat	0.4 0.3	1.0 0.3c	3.4 1.1a , c , d	2.1 0.7a , c , d
Magnesium mg/24 hours
Baseline	1.9 1.0	2.6 0.9	1.9 0.5	2.1 0.4
Diet	2.2 0.2	1.4 0.3a , c	0.7 0.3a , c , d	0.7 0.3a , c , d
Diet + orlistat	1.5 0.4	1.6 0.6a	0.5 0.2a , c , d	1.0 0.3a , c , d
Potassium mEq/L
Baseline	1.0 0.2	1.1 0.3	0.9 0.4	0.8 0.1
Diet	0.9 0.2	2.0 0.2a , c	1.5 0.8a , c	1.7 0.9a , c
Diet + orlistat	1.2 0.8	2.4 0.4a , c	2.1 0.8a , c	2.8 0.5a , b , c , d , e
Creatinine mg/24 hours
Baseline	6.2 1.4	8.3 1.0c	7.6 3.2c	8.0 1.9c
Diet	8.9 2.5a	11.0 2.0a , c , e	5.1 2.3	8.9 3.6a
Diet + orlistat	9.9 3.5a	10.5 0.9a , c	5.8 1.2	7.2 1.9d , e
pH
Baseline	6.9 0.3	6.3 0.3	6.7 0.1	6.6 0.2
Diet	6.8 0.4	6.6 0.4	7.0 0.8	6.5 0.8
Diet + orlistat	6.7 0.4	6.5 0.4	6.9 0.3	6.5 0.4

 Data are presented as mean SD.

 Comparison between periods.

^a  P < 0.05 vs. baseline

^b vs. diet.

 Comparison between groups: different from (P < 0.05)

^c vs. Control

^d vs. Soy Oil

^e vs. NaOx.