TABLE 3

FROM:

Impairment of phenylalanine conversion to tyrosine inend-stage renal disease causing tyrosine deficiency

YVES BOIRIE, ROBERT ALBRIGHT, MAUREEN BIGELOW and K SREEKUMARAN NAIR

Table 3. Baseline and amino acid–induced changes in plasma hormones

	Controls		End-stage renal disease (ESRD)
	Saline	Amino acid	Saline	Amino acid
Insulin	5.9 1.4	7.7 1.3	5.9 1.0	10.0 1.8
Glucagon	60.8 6.1	87.2 12.6	114.1 27.7a	181.3 49.2a
Cortisol	18.8 2.2	14.0 2.3	21.9 2.4	16.4 2.0
Growth hormone	0.19 0.11	1.22 0.50	0.75 0.28a	1.23 0.74
IGF free	0.73 0.20	0.67 0.15	1.29 0.46	1.07 0.30
IGF total	127 12	129 16	153 33	144 29
IGF-BP1	67.4 15.5	48.1 16.7	35.2 5.2a	19.0 7.6
IGF-BP3	2753 157	2757 185	4169 208b	4036 136b

 IGF is insulin-like growth factor. Mean SEM.

^a  P < 0.10 ESRD vs. control subjects.

^b  P < 0.01 ESRD vs. control subjects.