Kidney International

FIGURES AND TABLES

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Impairment of phenylalanine conversion to tyrosine inend-stage renal disease causing tyrosine deficiency

YVES BOIRIE, ROBERT ALBRIGHT, MAUREEN BIGELOW and K SREEKUMARAN NAIR

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

Figure 1.

Comparison of phenylalanine flux, tyrosine flux, and phenylalanine conversion to tyrosine (phenylalanine to tyrosine) during saline infusion and amino acid (AA) infusion. (A) Phenylalanine flux were not statistical significantly different between control and end-stage renal disease (ESRD) subjects and in both cases increase occurred with amino acid infusion. (B) Tyrosine flux was lower in ESRD patients than controls during saline and amino acid infusion. (C) Phenylalanine conversion to tyrosine was lower in ESRD patients than controls during saline and during amino acid infusion.

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Figure 2 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

Figure 2.

Comparison of phenylalanine conversion to tyrosine as a function of phenylalanine flux and phenylalanine concentration and tyrosine/phenylalanine ration in control and end-stage renal disease (ESRD) subjects. (A) Phenylalanine to tyrosine/phenylalanine flux. (B) Phenylalanine to tyrosine/phenylalanine concentration. (C) Tyrosine/phenylalanine. All these parameters were lower in ESRD patients than in the control subjects.

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Table 1 - Amino acid composition of aminosyn - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

Table 1 - Amino acid composition of aminosyn.

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Table 2 - Anthropometric, clinical, and biologic data of the population - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

Table 2 - Anthropometric, clinical, and biologic data of the population.

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Table 3 - Baseline and amino acid-induced changes in plasma hormones - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

Table 3 - Baseline and amino acid–induced changes in plasma hormones.

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Table 4 - Plasma amino acid concentrations during saline and during amino acid infusion - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

Table 4 - Plasma amino acid concentrations during saline and during amino acid infusion.

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