Kidney International

TABLE 4

FROM:

Effect of high dose ramipril with or without indomethacin on glomerular selectivity

Roberto Pisoni, Piero Ruggenenti, Fabio Sangalli, Maria Serena Lepre, Andrea Remuzzi and Giuseppe Remuzzi

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Table 4. Kidney functional parameters at baseline, at the end of ramipril titration phase (titration), at the maximum-tolerated ramipril dose (MR), at the indomethacin plus maximum-tolerated ramipril dose (MR+Ind), and after recovery

Figure and tables index
 BaselineTitrationMRMR+IndRecovery
GFR mL/min/1.73 m2 56plusminus3151plusminus2345plusminus25a b 50plusminus2848plusminus23a
RPF mL/min/1.73 m2 442plusminus280464plusminus241c 392plusminus209b 435plusminus269373plusminus220
FF % 14plusminus712plusminus4c 12plusminus412plusminus414plusminus6
Albumin FC times10-3 2.49plusminus1.831.72plusminus1.651.69plusminus1.091.86plusminus1.612.43plusminus1.73

 Data are mean plusminus SD. Abbreviations are: GFR, glomerular filtration rate; RPF, renal plasma flow; FF, filtration fraction; FC, fractional clearance.

a  P < 0.05 vs. baseline

b  P < 0.05 vs. titration

c  P < 0.05 vs. recovery

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