Kidney International

FIGURE 9

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Response of mesangial cells to low-density lipoprotein and angiotensin II in diabetic (OLETF) rats

Mitsuru Okada, Tsukasa Takemura, Hidehiko Yanagida and Kazuo Yoshioka

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Figure 9.

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DNA synthesis in OLETF and LETO MCs exposed to angiotensin II (Ang II 10-7 mol/L) for 18 hours. [3H]-thymidine incorporation was high in unstimulated y-OLETF MCs, and was further increased by exposure to Ang II, while it was low in o-LETF and LETO MCs with or without Ang II exposure. Symbols and bars represent means plusminus SE of 5 separate experiments (N = 3 rats per group); **P < 0.01.

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