Kidney International

FIGURE 5

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Response of mesangial cells to low-density lipoprotein and angiotensin II in diabetic (OLETF) rats

Mitsuru Okada, Tsukasa Takemura, Hidehiko Yanagida and Kazuo Yoshioka

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Figure 5.

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Uptake of fluorescence-labeled n-LDL into cultured MCs and binding of 125I-labeled n-LDL to cultured MCs. Dil-n-LDL-uptake (a) and binding to 125I-labeled n-LDL (b) were higher in y-OLETF MCs (c) than in o-OLETF or LETO MCs. Symbols and bars and bars represent means plusminus SE of 3 experiments, each carried out in quadruplicate. Symbols in panel d are: () y-OLETF; () y-LETO; (circle) o-LETO; () o-OLETF.

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