Kidney International

FIGURE 1

FROM:

PAI-1 deficiency attenuates the fibrogenic response to ureteral obstruction

Takashi Oda, Young Ok Jung, Heung Soo Kim, Xiaohe Cai, Jesús M López-Guisa, Yukiko Ikeda and Allison A Eddy

BACK TO ARTICLE

Figure 1.

Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

Sirius red staining of interstitial collagen fibrils. (A–D) These are from plasminogen-activator inhibitor-1 (PAI-1) wild-type (+/+) mice that were sham-operated (sham), and after 3, 7 and 14 days (3D, 7D, and 14D) of unilateral ureteral obstruction (UUO), respectively. (E–H) These are -/- sham, 3D, 7D, and 14D UUO, respectively (times400). (I) Data are mean plusminus 1 SD % of the interstitial area stained. Symbols are: (square) ++ mice; (filled square) -/- mice; *P < 0.05 compared with sham controls of the same genotype.

BACK TO ARTICLE