TABLE 1
FROM:
Idiopathic IgA nephropathy with segmental necrotizing lesions of the capillary wall
Giuseppe D'amico, Pietro Napodano, Franco Ferrario, Maria Pia Rastaldi and Girolamo Arrigo
BACK TO ARTICLETable 1. Histological and immunohistological lesions in 35 patients with necrotizing IgAN and in 229 patients with non-necrotizing IgAN
| Necrotizing IgAN | Non-necrotizing IgAN | P | |
|---|---|---|---|
| Number of patients | 35 | 229 | |
| Extracapillary proliferationa | 24.5% (8–53) | 4.5% (0–37) | <0.01 |
| Segmental glomerulosclerosisa | 5.2% (0–25) | 7.3% (0–57) | NS |
| Global glomerular sclerosisa | 15.8% (0–40) | 9.5% (0–44) | NS |
| Marked mesangial proliferationb | 40% | 36% | NS |
| Marked interstitial infiltrationb | 86% | 8% | <0.01 |
| Marked interstitial fibrosisb | 23% | 24% | NS |
| Combined mesangial and capillary deposition of IgA by IFb | 43% | 54% | NS |
a % of glomeruli (mean and range)
b % of biopsies
