FIGURE 8
FROM:
High glucose accelerates the life cycle of the in vivo exposed mesothelium
Avshalom Shostak, Valery Wajsbrot and Lazaro Gotloib
BACK TO ARTICLEFigure 8.
Our interpretation of the glucose-induced changes on the life cycle of the living and in situ-exposed mesothelial cell population. Normally, cells undergo two to three rounds of mitosis (upper part of the graphic) before reaching terminal differentiation and death in apoptosis. Early stimulation derived from exposure to a high concentration of glucose (lower part) induces acceleration of the cell cycle, multinucleation, accelerated senescence, and early activation of the mechanisms leading to apoptosis.
