TABLE 1

FROM:

Insulin-like growth factor system components in hyperparathyroidism and renal osteodystrophy

Peter M Jehle, Antje Ostertag, Klaus Schulten, Walter Schulz, Daniela R Jehle, Sylvia Stracke, Roman Fiedler, Heinz J Deuber, Frieder Keller, Bernhard O Boehm, David J Baylink and Subburaman Mohan

Table 1. Clinical data and laboratory findings (reference values in parentheses) in patients with primary hyperparathyroidism (pHPT) and different stages of chronic renal failure (CRF)

N	pHPT 25	CRF I° 29	CRF II° 48	CRF III° 37	ESRF/HD 148	ESRF/PD 27	ESRF/RTX 30 ( = 344)
Sex female/male	17/8	17/12	20/28	10/27	68/80	13/14	10/20
Age years	603 [23–83]	562.6 [21–79]	562.6 [26–82]	572.5 [20–82]	563 [17–84]	453a [21–75]	472a [24–66]
Duration of CRF years	—	3.10.6 [0.3–13]	5.91.2 [0.2–25]	6.90.8 [0.2–21]	7.40.6 [0.1–37]	9.41b [1–33]	12.31.2b, c [3–34]
Duration of HD, PD, or RTX years	—	—	—	—	4.40.4 [0.1–20]	5.20.5 [1–13]	7.00.6c [2–16]
Creatinine 58–110 mol/L	785	1608a [60–108]	35911a[111–245]	67527a [488–1114]	69220a [327–1353]	89850a [680–1541]	26332a, b, c [83–734]
Hemoglobin 12–15 g/dL	14.40.5 [12–15.8]	12.20.6a[11–15.3]>	11.40.3a[7.8–15.6]>	9.90.3a[7.3–14.6]>	9.80.2a[7–14.5]>	10.00.2a[7.5–13.2]>	12.10.4a, b, c[8.2–16.7]>
PTH 11–54 pg/mL	19335 [79–950]	14230 [14–627]	30340a [14–1365]	37437a [69–1135]	34530a [2–1470]	30957a [6–1174]	27345a, b [21–1160]
B-ALP 7–17 ng/mL	20.74 [4–68]	27.411 [3–38]	20.63 [3–63]	15.32 [6–53]	23.74 [4–353]	16.92 [5–51]	19.32 [5–424]
OSC 11–48 ng/mL	396 [7–135]	407 [4–115]	6613a [7–422]	16134a [8–958]	18539a [11–2280]	18671a [13–1602]	13771a [7–2244]
PICP 40–200 ng/mL	15716 [55–439]	17323 [81–531]	21322a [53–660]	21125a [66–675]	22415a [66–1066]	30028a [76–587]	26558a [88–529]
25-D3 10–60 ng/mL	18.72 [6–41]	18.33 [2–50]	24.44 [5–49]	27.66 [4–52]	30.35a [4–63]	15.63 [5–25]	18.12 [4–39]
1.25-D3 30–70 pg/mL	78.47 [22–138]	30.75a [3–67]	17.52a [5–31]	11.51a [5–25]	12.91a [0.6–50]	5.62a, b [3–12]	29.65a, b, c [1–56]

 Data are mean values [range] SEM. Abbreviations are in the Appendix.

^a  P < 0.05 vs. pHPT

^b  P < 0.05 vs. CRF III°

^c  P < 0.05 vs. PD