Meeting Report
Kidney International (1999) 56, S37–S40; doi:10.1046/j.1523-1755.56.s72.5.x
Acid-base balance and substitution fluid during continuous hemofiltration
Peter Heering, Katrin Ivens, Oliver Thümer, Matthias Braüse and Bernd Grabensee
Department of Nephrology, Heinrich-Heine-University of Düsseldorf, Düsseldorf, Germany
Correspondence: Peter Heering, M.D., Department of Nephrology and Rheumatology, Heinrich-Heine-University, 40001 Düsseldorf, Germany
Abstract
Acid-base balance during continuous hemofiltration in patients with acute renal failure. Critically ill patients with acute renal failure usually present with an unstable acid-base balance, often leading to cardiovascular complications and multi-organ failure. Therefore, to prevent metabolic acidosis, acid-base balance must be normalized and maintained; these patients are primarily treated with continuous hemofiltration techniques using different replacement fluids to influence the acid-base values. Dialysate solutions can be an acetate-based, lactate-based, citrate-based or bicarbonate-based buffer. This article discusses the strengths and weaknesses of each type of hemofiltration replacement fluid.
Keywords:
critical care, multi-organ failure, metabolic acidemia, acidosis, dialysate buffer


