FIGURE 1
FROM:
A laboratory model of toxin-induced hemolytic uremic syndrome
C Mark Taylor, Julie M Williams, Christopher J Lote, Alexander J Howie, Andrew Thewles, Jeanne A Wood, David V Milford, Faro Raafat, Ian Chant and Peter E Rose
BACK TO ARTICLEFigure 1.
(A) Glomeruli from rat treated with lipopolysaccharide (LPS) and ricin stained with an antifibrinogen antibody that has specifically detected thrombosis in glomerular capillaries (
1600). (B) Glomerulus from rat treated with ricin showing pyknotic nuclei in an endocapillary distribution (2400). (C) Frozen section of cortex treated with ricin-fluorescein isothiocyanate (FITC). The strongest binding is to distal tubules, particularly their basement membrane, and there is also binding to glomerular and intertubular capillaries, walls of arterioles, and the brush border of proximal tubules (1600). Publication of this figure in color was made possible by grants from Fujisawa Ltd. and Roche Pharmaceuticals UK.
