Kidney International

FIGURE 3

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Cyclosporine A induces apoptosis in murine tubular epithelial cells: Role of caspases

Alberto Ortiz, Corina Lorz, Marina Catalán, Arturo Ortiz, Santiago Coca and Jesus Egido

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Figure 3.

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CsA induces apoptosis of murine proximal tubular epithelial cells (MCT) in a time- and dose-dependent manner. (A) Time-response curve of apoptosis induced by 10 mug/ml CsA in serum-deprived MCT cells. (B) Dose response curve of apoptosis induced by exposure of serum-deprived cells to CsA for 72 hours. Mean plusminusSD of three independent experiments. * p ≷ 0.005 versus CsA alone.

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