Kidney International

FIGURE 3

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Elevated neointimal endothelin-1 in transplantation-associated arteriosclerosis of renal allograft recipients

Michael S Simonson, Steven N Emancipator, Thomas Knauss and Donald E Hricik

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Figure 3.

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Vascular expression of ET-1 in Tx-AA correlates with the Russell morphometric index of Tx-AA and with an index of hypertension. Densitometric values of ET-1 expression in the vasculature of patients with Tx-AA were correlated with a morphometric index that grades the severity of Tx-AA (A) and with an index that assess the severity of hypertension (B; Tables 1 and 2). Significant correlations (P < 0.01) were observed in both analyses. In A, r = 0.78, and in B, r = 0.82.

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