TABLE OF CONTENTS

Volume 53, Issue 6 (June 1998)

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Original Articles

Introduction FREE

Kidney Int 53: 1439-1440; doi:10.1046/j.1523-1755.1998.00923.x

Overview of strategies for complex genetic diseases FREE

Françoise Clerget-Darpoux

Kidney Int 53: 1441-1445; doi:10.1046/j.1523-1755.1998.00937.x

The relative power of linkage and association studies for the detection of genes involved in hypertension FREE

Hywel B Jones

Kidney Int 53: 1446-1448; doi:10.1046/j.1523-1755.1998.00925.x

Approaches to the genetics of cardiovascular disease through genetic field work FREE

Herbert Schuster, Anja Lamprecht, Christine Junghans, Birgit Dietz, Heike Baron, Michael Nothnagel, Bertram Müller-Myhsok and Friedrich C Luft

Kidney Int 53: 1449-1454; doi:10.1046/j.1523-1755.1998.00928.x

beta-2 Adrenoceptor genetic variation is associated with genetic predisposition to essential hypertension: The Bergen Blood Pressure Study FREE

Bernd Timmermann, Rune Mo, Friedrich C Luft, Eva Gerdts, Andreas Busjahn, Per Omvik, Guo-Hua Li, Herbert Schuster, Thomas F Wienker, Margret R Hoehe and Per Lund-Johansen

Kidney Int 53: 1455-1460; doi:10.1046/j.1523-1755.1998.00926.x

Role of genetic variants of the renin-angiotensin system in chronic renal allograft injury FREE

Arya M Sharma, Joachim Beige and Armin Distler

Kidney Int 53: 1461-1465; doi:10.1046/j.1523-1755.1998.00930.x

G proteins and hypertension: An alternative candidate gene approach FREE

Winfried Siffert

Kidney Int 53: 1466-1470; doi:10.1046/j.1523-1755.1998.00934.x

alpha-Adducin polymorphisms and renal sodium handling in essential hypertensive patients FREE

Paolo Manunta, Daniele Cusi, Cristina Barlassina, Marco Righetti, Chiara Lanzani, Marco D'Amico, Laura Buzzi, Lorena Citterio, Paola Stella, Rodolfo Rivera and Giuseppe Bianchi

Kidney Int 53: 1471-1478; doi:10.1046/j.1523-1755.1998.00931.x

Angiotensin I-converting enzyme and angiotensinogen gene interaction and prediction of essential hypertension FREE

Anna Vas caronku ring, Miroslav Souc caronek, Vladimír Znojil, Ivan R caronihác caronek, Svatava Tschöplová, Lenka Str caronelcová, Karel Cídl, Michaela Blaz caronková, Dobroslav Hájek, Lydie Hollá and Jir caroní Vácha

Kidney Int 53: 1479-1482; doi:10.1046/j.1523-1755.1998.00924.x

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Perspectives in Clinical Medicine

The Ob protein (leptin) and the kidney FREE

Kumar Sharma and Robert V. Considine

Kidney Int 53: 1483-1487; doi:10.1046/j.1523-1755.1998.00929.x

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Original Articles

Newborn and adult recombinant inbred strains: A tool to search for genetic determinants of target organ damage in hypertension FREE

Pavel Hamet, Zdenka Pausova, Pierre Dumas, Yu Lin Sun, Johanne Tremblay, Michal Pravenec, Jaroslav Kunes, Drahomira Krenova and Vladimir Kren

Kidney Int 53: 1488-1492; doi:10.1046/j.1523-1755.1998.00938.x

Genetic basis of salt-susceptibility in the Sabra rat model of hypertension FREE

Yoram Yagil and Chana Yagil

Kidney Int 53: 1493-1500; doi:10.1046/j.1523-1755.1998.00932.x

Is the nitric oxide system involved in genetic hypertension in Dahl rats? FREE

Alan Y Deng

Kidney Int 53: 1501-1511; doi:10.1046/j.1523-1755.1998.00933.x

The Wilms' tumor suppressor WT1: Approaches to gene function FREE

Aswin Menke, Lesley McInnes, Nicholas D Hastie and Andreas Schedl

Kidney Int 53: 1512-1518; doi:10.1046/j.1523-1755.1998.00935.x

Vascular development and disorders: Molecular analysis and pathogenic insights FREE

Peter Carmeliet and Désiré Collen

Kidney Int 53: 1519-1549; doi:10.1046/j.1523-1755.1998.00936.x

Antisense oligodesoxynucleotide strategies in renal and cardiovascular disease FREE

Hermann Haller, Christian Maasch, Duska Dragun, Maren Wellner, Michael von Janta-Lipinski and Friedrich C Luft

Kidney Int 53: 1550-1558; doi:10.1046/j.1523-1755.1998.00927.x

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Perspectives in Renal Medicine

Antihypertensive treatment of patients with proteinuric renal diseases: Risks or benefits of calcium channel blockers? FREE

Heinrich J Kloke, Amanda J Branten, Frans T Huysmans and Jack F Wetzels

Kidney Int 53: 1559-1573; doi:10.1046/j.1523-1755.1998.00912.x

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Perspectives in Basic Science

An appraisal of T cell subsets and the potential for autoimmune injury FREE

Carolyn J Kelly, Yaacov Frishberg and Daniel P Gold

Kidney Int 53: 1574-1584; doi:10.1046/j.1523-1755.1998.00917.x

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Genetic Disorders – Development

Expression of neuronal type nitric oxide synthase and renin in the juxtaglomerular apparatus of angiotensin type-1a receptor gene-knockout mice FREE

Minoru Kihara, Satoshi Umemura, Takeshi Sugaya, Yoshiyuki Toya, Machiko Yabana, Shunichi Kobayashi, Kovichi Tamura, Tetsuo Kadota, Reiji Kishida, Kazuo Murakami, Akiyoshi Fukamizu and Masao Ishii

Kidney Int 53: 1585-1593; doi:10.1046/j.1523-1755.1998.00904.x

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Original Articles

Spectrum of early onset nephrotic syndrome associated with WT1 missense mutations FREE

Valérie Schumacher, Karl Schärer, Elke Wühl, Hans Altrogge, Klaus-E Bonzel, Michael Guschmann, Thomas J Neuhaus, Rosa M Pollastro, Eberhard Kuwertz-Bröking, Monika Bulla, Andrea-M Tondera, Peter Mundel, Udo Helmchen, Rüdiger Waldherr, Angela Weirich and Brigitte Royer-Pokora

Kidney Int 53: 1594-1600; doi:10.1046/j.1523-1755.1998.00948.x

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Hormones – Cytokines – Signaling

TGF-beta1 dissociates human proximal tubule cell growth and Na+-H+ exchange activity FREE

David W Johnson, Heather J Saunders, Bronwyn K Brew, Philip Poronnik, David I Cook, Michael J Field and Carol A Pollock

Kidney Int 53: 1601-1607; doi:10.1046/j.1523-1755.1998.00916.x

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Original Articles

Protein overload stimulates RANTES production by proximal tubular cells depending on NF-kappaB activation FREE

Carla Zoja, Roberta Donadelli, Stella Colleoni, Marina Figliuzzi, Samantha Bonazzola, Marina Morigi and Giuseppe Remuzzi

Kidney Int 53: 1608-1615; doi:10.1046/j.1523-1755.1998.00905.x

Anti-latent TGF-beta binding protein-1 antibody or synthetic oligopeptides inhibit extracellular matrix expression induced by stretch in cultured rat mesangial cells FREE

Yuichi Hori, Tetsuo Katoh, Masao Hirakata, Nobuhiko Joki, Shinya Kaname, Masafumi Fukagawa, Toshihiro Okuda, Hideya Ohashi, Toshiro Fujita, Kohei Miyazono and Kiyoshi Kurokawa

Kidney Int 53: 1616-1625; doi:10.1046/j.1523-1755.1998.00908.x

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Cell Biology – Immunology – Pathology

Distinct HLA class II alleles determine antibody response to vaccination with hepatitis B surface antigen FREE

Sophie Caillat-Zucman, Jean-Jacques Gimenez, François Wambergue, Ginette Albouze, Bernard Lebkiri, Catherine Naret, Anne Moynot, Paul Jungers and Jean-François Bach

Kidney Int 53: 1626-1630; doi:10.1046/j.1523-1755.1998.00909.x

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Original Articles

Gene transfer of RANTES elicits autoimmune renal injury in MRL-Fas lpr mice FREE

Kathryn J Moore, Takashi Wada, Susannah D Barbee and Vicki Rubin Kelley

Kidney Int 53: 1631-1641; doi:10.1046/j.1523-1755.1998.00911.x

Effect of hypoxia on proximal tubules isolated from nitric oxide synthase knockout mice FREE

Hong Ling, Patricia E Gengaro, Charles L Edelstein, Pierre-Yves Martin, Adisorn Wangsiripaisan, Raphael Nemenoff and Robert W Schrier

Kidney Int 53: 1642-1646; doi:10.1046/j.1523-1755.1998.00913.x

Clusterin protects against oxidative stress in vitro through aggregative and nonaggregative properties FREE

Gary B Schwochau, Karl A Nath and Mark E Rosenberg

Kidney Int 53: 1647-1653; doi:10.1046/j.1523-1755.1998.00902.x

Effects of hypertonic stress on transforming growth factor-beta activity in normal rat kidney cells FREE

Toshihiro Sugiura, Atsushi Yamauchi, Hiroshi Kitamura, Yasuko Matusoka, Masaru Horio, Enyu Imai and Masatsugu Hori

Kidney Int 53: 1654-1660; doi:10.1046/j.1523-1755.1998.00903.x

Differential effects of glutathione and cysteine on Fe2+, Fe3+, H2O2 and myoglobin-induced proximal tubular cell attack FREE

Richard A Zager and Kristin M Burkhart

Kidney Int 53: 1661-1672; doi:10.1046/j.1523-1755.1998.00919.x

Meprin A, the major matrix degrading enzyme in renal tubules, produces a novel nidogen fragment in vitro and in vivo  FREE

Patrick D Walker, Gur P Kaushal and Sudhir V Shah

Kidney Int 53: 1673-1680; doi:10.1046/j.1523-1755.1998.00949.x

Verotoxins induce apoptosis in human renal tubular epithelium derived cells FREE

Tomoko Taguchi, Hiroshi Uchida, Nobutaka Kiyokawa, Tetsuya Mori, Norihide Sato, Hiroshi Horie, Tae Takeda and Junichiro Fujimoto

Kidney Int 53: 1681-1688; doi:10.1046/j.1523-1755.1998.00939.x

Cloning of a novel gene in the human kidney homologous to rat munc13s: Its potential role in diabetic nephropathy FREE

Yong Song, Menachem Ailenberg and Mel Silverman

Kidney Int 53: 1689-1695; doi:10.1046/j.1523-1755.1998.00942.x

Effect of 1,25(OH)2 vitamin D3 on glomerulosclerosis in subtotally nephrectomized rats FREE

Ute Schwarz, Kerstin Amann, Stephan R Orth, Aureliza Simonaviciene, Sabine Wessels and Eberhard Ritz

Kidney Int 53: 1696-1705; doi:10.1046/j.1523-1755.1998.00951.x

Mesangial cell hypertrophy induced by NH4Cl: Role of depressed activities of cathepsins due to elevated lysosomal pH FREE

Hong Ling, Pyam Ardjomand, Spiro Samvakas, Andreas Simm, Gillian L Busch, Florian Lang, Katarina Sebekova and August Heidland

Kidney Int 53: 1706-1712; doi:10.1046/j.1523-1755.1998.00952.x

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Ion channels – Membrane Transport – Integrative Physiology

Cadmium inhibits vacuolar H+-ATPase and endocytosis in rat kidney cortex FREE

Carol M Herak-Kramberger, Dennis Brown and Ivan Sabolic acute

Kidney Int 53: 1713-1726; doi:10.1046/j.1523-1755.1998.00914.x

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Original Articles

Identification of structural domains in inter-alpha-trypsin inhibitor involved in calcium oxalate crystallization FREE

Hiroshi Kobayashi, Kiyoshi Shibata, Michio Fujie, Dan Sugino and Toshihiko Terao

Kidney Int 53: 1727-1735; doi:10.1046/j.1523-1755.1998.00940.x

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Vascular Biology – Hemodynamics – Hypertension

Hypercholesterolemia aggravates radiocontrast nephrotoxicity: Protective role of L-arginine FREE

Lúcia Andrade, Sílvia B Campos and Antonio C Seguro

Kidney Int 53: 1736-1742; doi:10.1046/j.1523-1755.1998.00906.x

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Original Articles

Angiotensin converting enzyme gene I/D polymorphism in essential hypertension and nephroangiosclerosis FREE

Patricia Fernández-Llama, Esteban Poch, Josep Oriola, Albert Botey, Elisabet Coll, Alejandro Darnell, Francisca Rivera and Luis Revert

Kidney Int 53: 1743-1747; doi:10.1046/j.1523-1755.1998.00946.x

Role of increased oxygen free radical activity in the pathogenesis of uremic hypertension FREE

Nosratola D Vaziri, Fariba Oveisi and Yaoxian Ding

Kidney Int 53: 1748-1754; doi:10.1046/j.1523-1755.1998.00947.x

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Clinical Nephrology – Epidemiology – Clinical Trials

Renal involvement in Henoch-Schönlein purpura: A multivariate analysis of prognostic factors FREE

Yoshitsugu Kaku, Kaoru Nohara and Sunao Honda

Kidney Int 53: 1755-1759; doi:10.1046/j.1523-1755.1998.00915.x

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Original Articles

Expression of endothelial and inducible nitric oxide synthase in human glomerulonephritis FREE

Akira Furusu, Masanobu Miyazaki, Katsushige Abe, Shoko Tsukasaki, Kei Shioshita, Osamu Sasaki, Kenichi Miyazaki, Yoshiyuki Ozono, Takehiko Koji, Takashi Harada, Hideto Sakai and Shigeru Kohno

Kidney Int 53: 1760-1768; doi:10.1046/j.1523-1755.1998.00907.x

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Dialysis – Transplantation

Predictors of GBV-C infection among patients referred for renal transplantation FREE

B V R Murthy, A Scott Muerhoff, Suresh M Desai, Svetlozar N Natov, Beth A Bouthot, Robin Ruthazer, Christopher H Schmid, Andrew S Levey, Isa K Mushahwar and Brian J G Pereira

Kidney Int 53: 1769-1774; doi:10.1046/j.1523-1755.1998.00910.x

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Original Articles

Major determinants of hyperhomocysteinemia in peritoneal dialysis patients FREE

Andreas Vychytil, Manuela Födinger, Gabriele Wölfl, Brigitte Enzenberger, Martin Auinger, Friedrich Prischl, Martina Buxbaum, Martin Wiesholzer, Christine Mannhalter, Walter H Hörl and Gere Sunder-Plassmann

Kidney Int 53: 1775-1782; doi:10.1046/j.1523-1755.1998.00918.x

Perfusion quantitation in transplanted rat kidney by MRI with arterial spin labeling FREE

Jian-Jun Wang, Kristy S Hendrich, Edwin K Jackson, Suzanne T Ildstad, Donald S Williams and Chien Ho

Kidney Int 53: 1783-1791; doi:10.1046/j.1523-1755.1998.00945.x

Treatment of infected tunneled venous access hemodialysis catheters with guidewire exchange FREE

Derrick Robinson, Paul Suhocki and Steve J Schwab

Kidney Int 53: 1792-1794; doi:10.1046/j.1523-1755.1998.00954.x

Effects of balloon angioplasty and stent implantation on intrarenal echo-Doppler velocimetric indices FREE

Ivana Marana, Flavio Airoldi, Larry Burdick, Cristina Alberti, Andrea Lovaria, Silvia Saccheri, Gabriella Gazzano, Simone Palatresi, Barbara Nador, Lucia Turolo and Alberto Morganti

Kidney Int 53: 1795-1800; doi:10.1046/j.1523-1755.1998.00941.x

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Technical Note

RNA metabolism in uremic patients: Accumulation of modified ribonucleosides in uremic serum FREE

Toshimitsu Niwa, Naohito Takeda and Hideo Yoshizumi

Kidney Int 53: 1801-1806; doi:10.1046/j.1523-1755.1998.00944.x

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Editorial

Chemokines in interstitial injury FREE

Theodore M Danoff

Kidney Int 53: 1807-1808; doi:10.1046/j.1523-1755.1998.00920.x

GB virus-C (hepatitis G virus) nostalgia FREE

Kidney Int 53: 1809; doi:10.1046/j.1523-1755.1998.00953.x

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Nephrology Forum

Endothelial cell activation FREE

Barbara J Ballermann

Kidney Int 53: 1810-1826; doi:10.1046/j.1523-1755.1998.00943.x

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