Editorial Review

Kidney International (1991) 40, 583–596; doi:10.1038/ki.1991.249

Angiotensin actions in the kidney: Renewed insight into the old hormone

Iekuni Ichikawa1 and Raymond C Harris1

1Nashville, Tennessee, USA

Correspondence: Iekuni Ichikawa MD, Department of Pediatrics, Vanderbilt University Medical Center, 21st & Garland Avenues, Nashville, Tennessee 37232, USA.

Received 20 August 1990; Revised 28 January 1991; Accepted 29 January 1991.

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Abstract

Since the recognition of its potent vasoconstrictor action in the renal circulation, angiotensin II (Ang II) has several times come into the forefront in the nephrology community by revealing new biological actions which are seemingly unrelated to any of its previously recognized actions. Many of these actions have now been extensively studied (Table 1). Of interest, also, are its non-renal actions which are now known to be similarly rich in variety, thanks to extensive investigations on the central nervous and other organ systems.

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