Technical Note

Kidney International (1980) 18, 386–389; doi:10.1038/ki.1980.149

Techniques for use of charcoal hemoperfusion in infants: Experience in two patients

Blanche M Chavers1, Carl M Kjellstrand1, Clifford Wiegand1, James Ebben1 and S Michael Mauer1

1Departments of Pediatrics and Medicine, The University of Minnesota Medical School, Minneapolis, Minnesota

Correspondence: Dr B Chavers, Department of Pediatrics, Nephrology Division, Box 491, Mayo Memorial Bldg., University of Minnesota Hospitals, Minneapolis, Minnesota 55455, USA

Received 14 June 1979; Revised 6 December 1979.

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Abstract

Hemodialysis (HD) is used widely in the management of children with renal failure. The techniques and possible complications of HD treatment of infants and children have been well described [1], Charcoal hemoperfusion (CH) has received extensive use in adult patients for the adsorption of a variety of exogenous and endogenous intoxicants [2, 3]. Initially, CH resulted in complications such as thrombocytopenia, charcoal embolism, leukopenia, fibrinogenopenia, and hypocalcemia. The incidence of these complications has been reduced markedly by the use of polymer-coated charcoal [4, 5]. There has been, however, little pediatric experience in the use of CH. This paper indicates that the procedure can be safely adapted for use even in the newborn period.

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References

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